Recurrent multiple spinal paragangliomas as a manifestation of a metastatic composite paraganglioma-ganglioneuroblastoma

摘要

We describe the occurrence of multiple recurrent, aggressive spinal paragangliomas as the initial manifestation of a met-astatic composite paraganglioma-ganglioneuroblastoma in a 51-year-old patient.The patient developed progressive weakness and hypesthesia of both lower extremities. MRI demonstrated two intraspinal extradural lesions (Fig. la). A T4 and T6 hemilaminectomy was performed, and both intraspinal tumors were resected. During the postoperative period, the patient's neurological deficit significantly improved. Histology revealed a paraganglioma (Fig. lb, c).