Predicting asymptomatic cervical dilation in pregnant patients with short mid-trimester cervical length: A secondary analysis of a randomized controlled trial

摘要

Introduction Second trimester asymptomatic cervical dilation is a significant risk factor for early preterm birth. The objective of this study is to evaluate whether transvaginal ultrasound cervical length (CL) predicts asymptomatic cervical dilation on physical exam in women with short cervix (CL = 1 cm using receiver operating characteristic curve. Results In all, 119 women were included. Based on receiver operating characteristic curve, CL = 1 cm, with 75% sensitivity, 80% specificity, and area under the curve 0.73 (0.55-0.91), P = 0.009. Cervical length = 1 cm on physical exam (30% vs 3%, odds ratio 12.29 (3.05-49.37) P = 1 cm dilation had increased preterm birth 11 mm. Conclusions Among singletons without prior preterm birth diagnosed with short cervix (<= 25 mm), CL <= 11 mm may identify a subgroup of patients at high risk for asymptomatic cervical dilation and poor perinatal outcome. Physical exam should be considered and adjunctive preterm birth prevention measures should be studied in singletons with CL <= 11 mm.