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Physical activity and eye diseases. The Beijing Eye Study

机译:身体活动和眼病。 北京的眼睛研究

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Abstract Purpose To assess associations between the amount of physical activity and the prevalence of ocular diseases. Methods The participants of the population‐based Beijing Eye Study underwent a detailed ophthalmological examination and an interview. Physical activity was assessed in a standardized questionnaire. Results Out of 3468 study participants, information on their physical activity was available for 3031 (87.4%) individuals (age: 64.6?±?9.7?years; range: 50–93?years). In multivariate analysis (regression coefficient r : 0.41), higher physical activity was associated with a lower prevalence of diabetic retinopathy [p?=?0.009; standardized regression coefficient beta: ?0.05; non‐standardized regression coefficient B: ?15.7; 95% confidence interval ( CI ): ?27.6, ?3.90] after adjusting for younger age, rural region of habitation, lower level of education, lower blood concentrations of triglycerides and low‐density lipoproteins and higher blood concentrations of high‐density lipoproteins, higher systolic blood pressure, lower body mass index and lower depression score. Other major ocular diseases such as open‐angle glaucoma (p ? =?0.25), angle‐closure glaucoma (p ? =?0.59), nuclear cataract (p ? =?0.78), cortical cataract (p ? =?0.54), posterior subcapsular cataract (p ? =?0.96), retinal vein occlusions (p ? =?0.93) and central serous choroidopathy (p ? =?0.39) were not statistically associated with physical activity in that model. The association between higher physical activity and prevalence of age‐related macular degeneration (p ? =?0.04; β: 0.04; B: 4.87; 95% CI : 0.25, 9.50) was marginally significant. Conclusions Higher physical activity and less sedentary lifestyle were associated with a lower prevalence of diabetic retinopathy, while the occurrence of other major ocular diseases such as any type of cataract and of glaucoma, retinal vein occlusions and central serous choroidopathy was statistically independent of physical activity or a more sedentary lifestyle.
机译:摘要目的评估身体活动量与眼部疾病的患病率之间的关联。方法对北京人口的参与者进行了详细的眼科检查和面试。在标准化问卷中评估身体活动。在3468年的研究参与者中,有关其身体活动的信息可用于3031(87.4%)个体(年龄:64.6?±9.7?年;范围:50-93?年)。在多变量分析(回归系数R:0.41)中,较高的物理活性与糖尿病视网膜病变的较低率较低相关[p吗?= 0.009;标准化回归系数β:0.05;非标准化回归系数B:15.7; 95%置信区间(CI):?27.6,?3.90]调整年龄较小,农村地区的居住地,较低的教育水平,血液浓度降低,低密度脂蛋白和高密度脂蛋白的血液浓度高,收缩压较高,较低的体重指数和较低的抑郁分数。其他主要眼部疾病,如开角青光眼(p?= 0.25),角度闭合青光眼(p?= 0.59),核白内障(p?= 0.78),皮质白内障(p?= 0.54),后亚囊性白内障(P?= 0.96),视网膜静脉闭塞(P?= 0.93)和中央浆液脉络膜病(P?= 0.39)没有统计学相关,与该模型中的物理活性相关。较高身体活动与年龄相关性黄斑变性的患病率之间的关联(P?= 0.04;β:0.04; B:4.87; 95%CI:0.25,9.50)略微显着。结论较高的身体活动和更少的久坐不动的生活方式与糖尿病视网膜病变的较低率较低,而其他主要眼部疾病的发生如任何类型的白内障和青光眼,视网膜静脉闭塞和中央浆液脉络膜病症均无统计学上与身体活动无关或更久坐的生活方式。

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