bmp3 is Required for Integrity of Blood Brain Barrier by Promoting Pericyte Coverage in Zebrafish Embryos

Lei D.; Jin X.; Wen L.; Dai H.; Ye Z.; Wang G.

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bmp3 is Required for Integrity of Blood Brain Barrier by Promoting Pericyte Coverage in Zebrafish Embryos

机译：通过促进斑马鱼胚胎中的细胞覆盖，血脑屏障的完整性是BMP3所必需的

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Background: The compromise of blood brain barrier (BBB) integrity is often associated with human hemorrhage stroke and neurodegeneration diseases, including retina diseases, such as age-related macular degeneration and diabetic retinopathy. Brain pericytes play pivotal roles in regulation and maintenance of BBB integrity. However, the mechanisms underlying brain pericyte development to establish BBB integrity remain unclear.

机译：背景：血脑屏障（BBB）完整性的折衷通常与人出血中风和神经变性疾病有关，包括视网膜疾病，如年龄相关的黄斑变性和糖尿病视网膜病变。脑周细胞在BBB完整性的调节和维护中发挥关键作用。然而，脑周性发展的机制仍然不清楚。

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《Current molecular medicine》 |2017年第4期|共6页
作者
Lei D.; Jin X.; Wen L.; Dai H.; Ye Z.; Wang G.;
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作者单位

Chongqing Univ Key Lab Biorheol Sci &

Technol State &

Local Joint Engn Lab Vasc Implants Bioengn;

Chongqing Univ Key Lab Biorheol Sci &

Technol State &

Local Joint Engn Lab Vasc Implants Bioengn;

Chongqing Univ Key Lab Biorheol Sci &

Technol State &

Local Joint Engn Lab Vasc Implants Bioengn;

Chongqing Univ Key Lab Biorheol Sci &

Technol State &

Local Joint Engn Lab Vasc Implants Bioengn;

Chongqing Univ Key Lab Biorheol Sci &

Technol State &

Local Joint Engn Lab Vasc Implants Bioengn;

Chongqing Univ Key Lab Biorheol Sci &

Technol State &

Local Joint Engn Lab Vasc Implants Bioengn;

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原文格式 PDF
正文语种 eng
中图分类分子生物学;
关键词
Blood brain barrier (BBB); bmp3; pericyte; permeability; hemorrhage; zebrafish;

机译：血脑屏障（BBB）;BMP3;周刊;渗透率;出血;斑马鱼;

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专利

1. bmp3 is Required for Integrity of Blood Brain Barrier by Promoting Pericyte Coverage in Zebrafish Embryos [J] . Lei D., Jin X., Wen L., Current molecular medicine . 2017,第4期

机译：通过促进斑马鱼胚胎中的细胞覆盖，血脑屏障的完整性是BMP3所必需的
2. The impact of pericytes on the blood-brain barrier integrity depends critically on the pericyte differentiation stage. [J] . Thanabalasundaram G, Schneidewind J, Pieper C, The international journal of biochemistry and cell biology . 2011,第9期

机译：周细胞对血脑屏障完整性的影响主要取决于周细胞分化阶段。
3. Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier [J] . Reyahi Azadeh, Nik Ali M., Ghiami Mozhgan, Developmental cell . 2015,第1期

机译：Foxf2是脑周细胞分化，血脑屏障的发展和维持所必需的。
4. Peptide-22 and cRGD functionalized liposomes for targeted delivery of doxorubicin to glioma through the blood-brain barrier and blood-brain tumor barrier [C] . A.Cuitian Chen, B.Ziqing Duan, C.Jianxin Wang International Forum on Leading Edge Technologies on Crystallization Engineering and Pharmaceutics Development;Tianjin University;Tianjin Medical University . -1

机译：肽-22和CRGD官能化脂质体通过血脑屏障和血脑肿瘤屏障对胶质瘤的靶向递送到胶质瘤
5. Examining the integrity of the blood-brain barrier (BBB) and the use of lysophosphatidic acid (LPA) to modulate the barrier properties. [D] . On, Ngoc H. 2012

机译：检查血脑屏障（BBB）的完整性以及使用溶血磷脂酸（LPA）调节屏障的性质。
6. Pericytes are required for blood–brain barrier integrity during embryogenesis [O] . Richard Daneman, Lu Zhou, Amanuel A. Kebede, -1

机译：周细胞胚胎发育过程中所需的血 - 脑屏障的完整性
7. Pericytes are required for blood–brain barrier integrity during embryogenesis [O] . Richard Daneman, Lu Zhou, Amanuel A. Kebede, 2010

机译：在胚胎发生期间血脑屏障完整性需要血细胞

bmp3 is Required for Integrity of Blood Brain Barrier by Promoting Pericyte Coverage in Zebrafish Embryos

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