Liposomes Containing Gadodiamide: Preparation, Physicochemical Characterization, and In Vitro Cytotoxic Evaluation

Chaves Maia Ana Luiza; Fernandes Christian; Pereira de Oliveira Cynthia Nara; Teixeira Claudia Salviano; Oliveira Mariana Silva; Ferreira Soares Daniel Cristian; Ramaldes Gilson Andrade

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Liposomes Containing Gadodiamide: Preparation, Physicochemical Characterization, and In Vitro Cytotoxic Evaluation

机译：含有青二胺的脂质体：制备，物理化学表征和体外细胞毒性评价

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摘要

Background: The aim of this study was to develop, characterize and assess the cytotoxic activity of pHsensitive (pHL-Gd), stealth pH-sensitive (SpHL-Gd), and conventional (convL-Gd) liposomes containing gadodiamide (Gd-DTPA-BMA).

机译：背景：本研究的目的是发展，表征和评估phsisispitive（phl-gd）的细胞毒性活性，隐形pH敏感（sphl-gd）和含有钆胺的常规（convl-gd）脂质体（gd-dtpa- BMA）。

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来源
《Current drug delivery 》 |2017年第4期| 共9页
作者
Chaves Maia Ana Luiza; Fernandes Christian; Pereira de Oliveira Cynthia Nara; Teixeira Claudia Salviano; Oliveira Mariana Silva; Ferreira Soares Daniel Cristian; Ramaldes Gilson Andrade;
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作者单位

Univ Fed Minas Gerais Fac Pharm Dept Pharmaceut Prod Belo Horizonte MG Brazil;

Univ Fed Minas Gerais Fac Pharm Dept Pharmaceut Prod Belo Horizonte MG Brazil;

Univ Fed Minas Gerais Fac Pharm Dept Pharmaceut Prod Belo Horizonte MG Brazil;

Univ Fed Minas Gerais Fac Pharm Dept Pharmaceut Prod Belo Horizonte MG Brazil;

Univ Fed Minas Gerais Fac Pharm Dept Pharmaceut Prod Belo Horizonte MG Brazil;

Fed Univ Itajub Rua Irma Ivone Drumond 200 Dist Ind 2 BR-35903087 Itabira MG Brazil;

Univ Fed Minas Gerais Fac Pharm Dept Pharmaceut Prod Belo Horizonte MG Brazil;

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原文格式 PDF
正文语种 eng
中图分类药学 ;
关键词
Antineoplastic agent; cancer treatment; 4T1 breast cancer cell line; Gd-DTPA-BMA; in vitro cytotoxic evaluation; liposomes;

机译：抗肿瘤剂;癌症治疗;4T1乳腺癌细胞系;GD-DTPA-BMA;体外细胞毒性评价;脂质体;

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专利

1. Liposomes Containing Gadodiamide: Preparation, Physicochemical Characterization, and In Vitro Cytotoxic Evaluation [J] . Chaves Maia Ana Luiza, Fernandes Christian, Pereira de Oliveira Cynthia Nara, Current drug delivery . 2017 ,第4期

机译：含有青二胺的脂质体：制备，物理化学表征和体外细胞毒性评价
2. Liposomes radiolabeled with 159Gd-DTPA-BMA: preparation, physicochemical characterization, release profile and in vitro cytotoxic evaluation. [J] . Soares DC, de Oliveira MC, dos Santos RG, European journal of pharmaceutical sciences . 2011 ,第5期

机译：用159Gd-DTPA-BMA放射性标记的脂质体：制备，理化特性，释放曲线和体外细胞毒性评估。
3. Stavudine loaded gelatin liposomes for HIV therapy: Preparation, characterization and in vitro cytotoxic evaluation [J] . Debasis Nayak, Ankita Boxi, Sarbani Ashe, Materials science & engineering . 2017 ,第APRa期

机译：stavudine负载明胶脂质体用于HIV治疗：制备，表征和体外细胞毒性评估
4. Preparation, characterization and in vitro cytotoxicity of solid lipid nanoparticles loaded with doxorubicin [C] . S. F. Taveira, N. Auro, R. F. V. Lopez Annual meeting exposition of the Controlled Release Society . 2009

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5. Characterization of thermosensitive hybrid archaeosomes and DPA-Cy[22,22]/POPC liposomes and in vitro evaluation of their potential usefulness in targeted delivery and controlled release. [D] . Ayesa, Umme. 2016

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6. Evaluation of octyl p-methoxycinnamate included in liposomes and cyclodextrins in anti-solar preparations: preparations characterizations and in vitro penetration studies [O] . Mariana Sato de Souza de Bustamante Monteiro, Rafael Antonio Ozzetti, André Luiz Vergnanini, 2012

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Liposomes Containing Gadodiamide: Preparation, Physicochemical Characterization, and In Vitro Cytotoxic Evaluation

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