Risk Factors for and Clinical Management of Venous Thromboembolism During Pregnancy

摘要

Venous thromboembolism (VTE), which encompasses deep vein thrombosis (DVT) and pulmonary embolism (PE), is among the leading causes of non-obstetric maternal death in the United States and other developed nations.1'2 VTE is responsible for 9.2% of maternal deaths in the United States, with an observed increase in VTE incidence during hospitalization for vaginal delivery from 15.6 per 100,000 deliveries in 2006 to 29.8 per 100,000 deliveries in 2012.3'4 The VTE risk increases by 4- to 6-fold during pregnancy, and is highest in the immediate postpartum period.5'6