Ga-68-DOTA-TATE in Neuroblastoma With Marrow Involvement

摘要

A 22-month-old boy diagnosed with neuroblastoma was evaluated by bone scintigraphy and I-123-metaiodobenzylguanidine scintigraphy, and no metastases to skeletal system was detected. However, plain radiograph and MRI revealed suspected metastatic lesions. The patient was therefore evaluated by Ga-68-DOTA-TATE PET/CT, and Ga-68-DOTA-TATE uptake was observed in multiple bone and bone marrow areas, which were consistent with metastases. Biopsy was taken from the right iliac bone, and the pathological examination of the biopsy specimen was coherent with neuroblastoma invasion.