Pharmacokinetic and Pharmacodynamic Characteristics of Vancomycin and Meropenem in Critically Ill Patients Receiving Sustained Low-efficiency Dialysis

Oliveira Maura Salaroli; Machado Anna Silva; Mendes Elisa Teixeira; Chaves Lucas; Perdigao Neto Lauro Vieira; da Silva Jr Carlindo Vieira; Cavani Jorge Santos Silvia Regina; Sanches Cristina; Macedo Etienne; Levin Anna S.

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Pharmacokinetic and Pharmacodynamic Characteristics of Vancomycin and Meropenem in Critically Ill Patients Receiving Sustained Low-efficiency Dialysis

机译：患有持续低效率透析的危重病患者的万古霉素和梅洛涅姆的药代动力学和药物动力学特征

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Purpose: Antibiotic dosing is challenge in critically ill patients undergoing renal replacement therapy. Our aim was to evaluate the pharmacokinetic and pharmacodynamic (PK/PD) characteristics of meropenem and vancomycin in patients undergoing SLED.

机译：目的：抗生素给药在肾脏替代疗法的重症患者中是挑战性的。我们的目的是评估Meropenem和Vachomycin的药代动力学和药物动力学（PK / PD）特征在接受雪橇患者中。

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来源
《Clinical therapeutics》 |2020年第4期|共9页
作者
Oliveira Maura Salaroli; Machado Anna Silva; Mendes Elisa Teixeira; Chaves Lucas; Perdigao Neto Lauro Vieira; da Silva Jr Carlindo Vieira; Cavani Jorge Santos Silvia Regina; Sanches Cristina; Macedo Etienne; Levin Anna S.;
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作者单位

Univ Sao Paulo Clin Hosp Fac Med Dept Infect Control Sao Paulo Brazil;

Univ Sao Paulo Clin Hosp Fac Med Dept Infect Control Sao Paulo Brazil;

Univ Sao Paulo Clin Hosp Fac Med Dept Infect Control Sao Paulo Brazil;

Univ Sao Paulo Clin Hosp Fac Med Dept Infect Control Sao Paulo Brazil;

Univ Sao Paulo Clin Hosp Fac Med Dept Infect Control Sao Paulo Brazil;

Univ Sao Paulo Sch Pharmaceut Sci Sao Paulo Brazil;

Univ Sao Paulo Sch Pharmaceut Sci Sao Paulo Brazil;

Univ Fed Sao Joao del Rei Sao Joao Del Rei Brazil;

Univ Calif San Diego Dept Med Div Nephrol San Diego CA 92103 USA;

Univ Sao Paulo Clin Hosp Fac Med Dept Infect Control Sao Paulo Brazil;

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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
critical care; dialysis; drug monitoring; meropenem; vancomycin;

机译：关键护理;透析;药物监测;梅洛尼霉素;万古霉素;

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专利

1. Pharmacokinetic and Pharmacodynamic Characteristics of Vancomycin and Meropenem in Critically Ill Patients Receiving Sustained Low-efficiency Dialysis [J] . Oliveira Maura Salaroli, Machado Anna Silva, Mendes Elisa Teixeira, Clinical therapeutics . 2020,第4期

机译：患有持续低效率透析的危重病患者的万古霉素和梅洛涅姆的药代动力学和药物动力学特征
2. Vancomycin Population Pharmacokinetics in Critically Ill Adults During Sustained Low-Efficiency Dialysis [J] . Kanji Salmaan, Roberts Jason A., Xie Jiao, Clinical pharmacokinetics . 2020,第3期

机译：持续低效率透析期间批判性成年人的万古霉素群体药代动力学
3. Meropenem removal in critically ill patients undergoing sustained low-efficiency dialysis (SLED) [J] . Ladan Golestaneh Nephrology Dialysis Transplantation . 2010,第8期

机译：接受持续低效透析（SLED）的危重患者的美罗培南去除
4. Heart rate variability as an indicator for morphine pharmacokinetics and pharmacodynamics in critically ill newborn infants [C] . Bressan Nadja, McGregor Carolyn, Smith Kathy, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2014

机译：心率变异性是危重新生儿中吗啡药代动力学和药效学的指标
5. Bioanalysis and pharmacokinetics-pharmacodynamics modeling of the endogenous 2'deoxynucleoside triphosphate pool in individuals receiving tenofovir/emtricitabine. [D] . Chen, Xinhui. 2016

机译：接受替诺福韦/恩曲他滨治疗的个体中内源性2'脱氧核苷三磷酸池的生物分析和药代动力学-药效学建模。
6. Pharmacokinetics of meropenem in septic patients on sustained low-efficiency dialysis: a population pharmacokinetic study [O] . Stephan Braune, Christina König, Jason A. Roberts, 2018

机译：美洛培南在持续低效率透析中对败血病患者的药代动力学：一项群体药代动力学研究
7. Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis [O] . Christina König, Stephan Braune, Jason A. Roberts, 2017

机译：治疗持续低效率透析的危重病患者的头孢他犯中种群药代动力学和剂量模拟
8. Serum Vancomycin Levels Resulting from Continuous or Intermittent Infusion in Critically Ill Burn Patients With or Without Continuous Renal Replacement Therapy. [R] . Akers, K. S., Cota, J. M., Chung, K. K., 2012

机译：连续或间歇性输注的血清万古霉素水平在有或没有连续肾脏替代疗法的重症烧伤患者中。

Pharmacokinetic and Pharmacodynamic Characteristics of Vancomycin and Meropenem in Critically Ill Patients Receiving Sustained Low-efficiency Dialysis

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