Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals

Chang Leon; Daly Catherine; Miller Dorota M.; Allen Paul D.; Boyle John P.; Hopkins Philip M.; Shaw Marie-Anne

首页> 外文期刊>British journal of anaesthesia >Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals

【24h】

Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals

机译：透氧骨骼肌揭示了恶性肿瘤易感性的线粒体缺乏

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Background: Individuals genetically susceptible to malignant hyperthermia (MH) exhibit hypermetabolic reactions when exposed to volatile anaesthetics. Mitochondrial dysfunction has previously been associated with the MH-susceptible (MHS) phenotype in animal models, but evidence of this in human MH is limited.

机译：背景：在暴露于挥发性麻醉剂时，遗传易于恶性热疗（MH）的个体易于患过高代谢反应。线粒体功能障碍先前已与动物模型中的MH易感（MHS）表型相关联，但在人MH中的证据是有限的。

著录项

来源
《British journal of anaesthesia》 |2019年第5期|共9页
作者
Chang Leon; Daly Catherine; Miller Dorota M.; Allen Paul D.; Boyle John P.; Hopkins Philip M.; Shaw Marie-Anne;
展开▼
作者单位

Univ Leeds Leeds Inst Med Res St Jamess Leeds W Yorkshire England;

St James Univ Hosp Malignant Hyperthermia Unit Leeds W Yorkshire England;

Univ Leeds Leeds Inst Med Res St Jamess Leeds W Yorkshire England;

Univ Leeds Leeds Inst Med Res St Jamess Leeds W Yorkshire England;

Univ Leeds Leeds Inst Cardiovasc &

Metab Med Leeds W Yorkshire England;

Univ Leeds Leeds Inst Med Res St Jamess Leeds W Yorkshire England;

Univ Leeds Leeds Inst Med Res St Jamess Leeds W Yorkshire England;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类麻醉学;
关键词
electron transport chain; malignant hyperthermia; mitochondria; oxidative phosphorylation; skeletal muscle; volatile anaesthetic;

机译：电子传输链;恶性热疗;线粒体;氧化磷酸化;骨骼肌;挥发性麻醉;
入库时间 2022-08-19 23:17:34

相似文献

外文文献
中文文献
专利

1. Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals [J] . Chang Leon, Daly Catherine, Miller Dorota M., British journal of anaesthesia . 2019,第5期

机译：透氧骨骼肌揭示了恶性肿瘤易感性的线粒体缺乏
2. Basal Bioenergetic Abnormalities in Skeletal Muscle from Ryanodine Receptor Malignant Hyperthermia-susceptible R163C Knock-in Mice [J] . Cecilia Giulivi, Catherine Ross-Inta, Alicja Omanska-Klusek, The Journal of biological chemistry . 2011,第1期

机译：瑞尼诺受体恶性热疗易感性R163C敲击小鼠骨骼肌基础生物能量异常
3. Store-operated Ca2+ Entry in Malignant Hyperthermia-susceptible Human Skeletal Muscle [J] . Adrian Duke, Philip Hopkins, Sarah Calaghan, The Journal of biological chemistry . 2010,第33期

机译：储存的CA2 +在恶性热疗中的入口易受人体骨骼肌
4. Interaction between adipose tissue and skeletal muscle in the control of muscle mitochondrial functions [C] . E. Chanseaume, P. Rousset, C. Gryson, International Symposium on Energy and Protein Metabolism and Nutrition . 2007

机译：脂肪组织与骨骼肌对肌肉线粒体函数控制之间的相互作用
5. Effects of High-Insulin Exposure on Mitochondrial Content in Skeletal Muscle Myotubes from Lean & Severely Obese Individuals: A Time Course Analysis. [D] . Turner, Kristen D. 2016

机译：高胰岛素暴露对瘦和重度肥胖个体骨骼肌肌管线粒体含量的影响：时程分析。
6. Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals [O] . Leon Chang, Catherine Daly, Dorota M. Miller, -1

机译：透化骨骼肌揭示了恶性高热易感个体的线粒体缺乏
7. Basal Bioenergetic Abnormalities in Skeletal Muscle from Ryanodine Receptor Malignant Hyperthermia-susceptible R163C Knock-in Mice* [O] . Giulivi, Cecilia, Ross-Inta, Catherine, Omanska-Klusek, Alicja, 2010

机译：Ryanodine受体恶性高热易感性R163C敲入小鼠的骨骼肌基本生物能异常*
8. Influence of Dietary Iron Deficiency on Hemoglobin, Myoglobin, Their Respective Reductases, and Skeletal Muscle Mitochondrial Respiration [R] . Hagler, L., Askew, E. W., Neville, J. R., 1981

机译：膳食铁缺乏对血红蛋白，肌红蛋白及其各自的还原酶和骨骼肌线粒体呼吸的影响

Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals

摘要

著录项

相似文献

相关主题

期刊订阅