Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants

Sohn Jin A.; Kim Han-Suk; Oh Jaeseong; Cho Joo-Youn; Yu Kyung-Sang; Lee Juyoung; Shin Seung Han; Lee Jin A.; Choi Chang Won; Kim Ee-Kyung; Kim Beyong Il; Park Eun Ae

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Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants

机译：预测早产儿尿代谢物血清茶碱浓度和细胞色素P4501A2活性

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《British Journal of Clinical Pharmacology》 |2017年第6期|共8页
作者
Sohn Jin A.; Kim Han-Suk; Oh Jaeseong; Cho Joo-Youn; Yu Kyung-Sang; Lee Juyoung; Shin Seung Han; Lee Jin A.; Choi Chang Won; Kim Ee-Kyung; Kim Beyong Il; Park Eun Ae;
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作者单位

Seoul Natl Univ Coll Med Dept Pediat 101 Deahak Ro Seoul 03080 South Korea;

Seoul Natl Univ Coll Med Dept Pediat 101 Deahak Ro Seoul 03080 South Korea;

Seoul Natl Univ Coll Med &

Hosp Dept Clin Pharmacol &

Therapeut Seoul South Korea;

Seoul Natl Univ Coll Med &

Hosp Dept Clin Pharmacol &

Therapeut Seoul South Korea;

Seoul Natl Univ Coll Med &

Hosp Dept Clin Pharmacol &

Therapeut Seoul South Korea;

Seoul Natl Univ Coll Med Dept Pediat 101 Deahak Ro Seoul 03080 South Korea;

Seoul Natl Univ Coll Med Dept Pediat 101 Deahak Ro Seoul 03080 South Korea;

Seoul Natl Univ Coll Med Dept Pediat 101 Deahak Ro Seoul 03080 South Korea;

Seoul Natl Univ Coll Med Dept Pediat 101 Deahak Ro Seoul 03080 South Korea;

Seoul Natl Univ Coll Med Dept Pediat 101 Deahak Ro Seoul 03080 South Korea;

Seoul Natl Univ Coll Med Dept Pediat 101 Deahak Ro Seoul 03080 South Korea;

Ewha Womans Univ Sch Med Dept Pediat Seoul South Korea;

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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
cytochrome P450 1A2; drug monitoring; pharmacokinetics; premature infants; theophylline;

机译：细胞色素p450 1a2;药物监测;药代动力学;早产儿;茶碱;

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专利

1. Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants [J] . Jin A Sohn, Han‐Suk Kim, Jaeseong Oh, British journal of clinical pharmacology . 2017,第6期

机译：通过分析早产儿尿中代谢产物预测血清茶碱浓度和细胞色素P450 1A2活性
2. Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants [J] . Sohn Jin A., Kim Han-Suk, Oh Jaeseong, British Journal of Clinical Pharmacology . 2017,第6期

机译：预测早产儿尿代谢物血清茶碱浓度和细胞色素P4501A2活性
3. Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants [J] . Sohn Jin A., Kim Han-Suk, Oh Jaeseong, British Journal of Clinical Pharmacology . 2017,第6期

机译：预测早产儿尿代谢物血清茶碱浓度和细胞色素P4501A2活性
4. Mice lacking the Cytochrome P450 (CYP)1A2 Gene Display Increased Levels of F2-Isoprostanes, Oxidative DNA Adducts, and Hyperoxic Lung Injury In Vivo [C] . Moorthy B., Wang L., Couroucli X. I., International Conference on Cytochrome P450 . 2009

机译：缺乏细胞色素P450（CYP）1A2基因的小鼠显示出增加的F2 - 依泊司蛋白，氧化DNA加合物和体内高氧肺损伤水平
5. Immobilized Cytochrome P450 2C9 (CYP2C9): Applications for Metabolite Generation, Monitoring Protein-Protein Interactions, and Improving In-vivo Predictions Using Enhanced In-vitro Models [D] . Wollenberg, Lance A. 2011

机译：固定化细胞色素P450 2C9（CYP2C9）：用于代谢物生成，监测蛋白质-蛋白质相互作用以及使用增强的体外模型改善体内预测的应用
6. Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants [O] . Jin A Sohn, Han‐Suk Kim, Jaeseong Oh, 2017

机译：通过分析早产儿尿中代谢产物预测血清茶碱浓度和细胞色素P450 1A2活性
7. Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants [O] . Jin A Sohn, Han-Suk Kim, Jaeseong Oh, 2017

机译：预测早产儿尿代谢物血清茶碱浓度和细胞色素P4501A2活性
8. Comparative Ability of Various PCBs, PCDFs, and TCDD to Induce Cytochrome P4501A1 and 1A2 Activity Following 4 Weeks of Treatment (Short Communication) [R] . De Vito, M. J., Maier, W. E., Diliberto, J. J., 1993

机译：各种pCBs，pCDFs和TCDD在4周治疗后（短交流）诱导细胞色素p4501a1和1a2活性的比较能力

Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants

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