Relationship of histologic grade and histologic subtype with oncotype Dx recurrence scoreI3/4 retrospective review of 863 breast cancer oncotype Dx results

摘要

Oncotype Dx (ODx) is a multigene assay that is prognostic and predictive in estrogen receptor (ER) positive early breast cancer. ODx recurrence score (RS) is reported to be histologic grade dependent. Relationship of RS with breast cancer histologic subtypes is unknown. This study was designed to assess the relationship of histologic subtype with RS. Histologic grade dependence of RS was also investigated.