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Proposal of 28?GHz In Vitro Exposure System Based on Field Uniformity for Three‐Dimensional Cell Culture Experiments

机译:基于三维细胞培养实验的现场均匀性的28?GHz在体外暴露系统

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This paper proposes a novel in vitro exposure system operating at millimeter‐wave (mmWave) 28?GHz, one of the frequency bands under consideration for fifth generation (5G) communication. We employed the field uniformity concept along cross‐sectional observation planes at shorter distances from the radiation antenna for better efficiency and a small‐size system. A choke‐ring antenna was designed for this purpose in consideration of a wider beamwidth (BW) and a symmetric far‐field pattern across three principal planes. The permittivity of Dulbecco's modified Eagle's medium solution was measured to examine the specific absorption rate (SAR) of the skin cell layer inside a Petri dish model for a three‐dimensional (3D) cell culture in vitro experiment. The best deployment of Petri dishes, taking into account a geometrical field symmetry, was proposed. Local SAR values within the cell layer among the Petri dishes were determined with different polarization angles. It was determined that this polarization effect should be considered when the actual exposure and deployment were conducted. We finally proposed an in vitro exposure system based on the field uniformity including downward exposure from an antenna for 3D cell culture experiments. A small‐size chamber system was obtained, and the size was estimated using the planar near‐field chamber design rule. Bioelectromagnetics. 2019;40:445–457. ? 2019 Bioelectromagnetics Society
机译:本文提出了一种在毫米波(MMWAVE)28πGHz的体外曝光系统的新型体外曝光系统,其考虑第五代(5G)通信的频带之一。我们沿着横截面观察平面沿着辐射天线的距距离沿横截面观察平面采用现场均匀性概念,以获得更好的效率和小尺寸的系统。考虑到三个主要平面的更宽的波束(BW)和对称的远场模式,设计了一个扼流圈天线。测量Dulbecco改性鹰培养基溶液的介电常数,以检查在体外实验中的三维(3D)细胞培养的培养皿模型内皮肤细胞层的特定吸收率(SAR)。提出了考虑到几何场对称的培养皿的最佳部署。用不同的偏振角确定培养皿中的细胞层内的局部SAR值。确定在进行实际曝光和部署时应考虑这种偏振效应。我们终于提出了一种基于现场均匀性的体外曝光系统,包括从天线向3D细胞培养实验向下曝光。获得了小尺寸的室系统,使用平面近场室设计规则估计大小。生物电磁学。 2019; 40:445-457。还2019生物电磁学会

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