A novel magnetic drug delivery nanocomplex with a cisplatin-conjugated Fe3O4 core and a PEG-functionalized mesoporous silica shell for enhancing cancer drug delivery efficiency

摘要

Towards the rapid synthesis and efficient action of a smart drug delivery nanosystem based on coating a layer of PEG functionalized mesoporous silica onto a cisplatin (CDDP) conjugated Fe3O4 nanocomposite. We achieve a number of nanocomplex enhancements of the biomagnetic carriers' therapeutic functionality. Such a novel drug-delivery nanosystem has potential applications in cancer treatment.