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A simple method for fabrication of microfluidic paper-based analytical devices and on-device fluid control with a portable corona generator

机译:一种简单的制造微流体纸的分析装置和装置用便携式电晕发电机的装置流体控制方法

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摘要

This work presents a facile method for fabrication of microfluidic paper-based analytical devices (mu PADs) and on-device fluid control with a portable, hand-held corona generator. First, filter paper was hydrophobized by coupling octadecyltrichlorosilane (OTS) to paper cellulose. Then, the OTS-coated paper, covered with a stenciled plastic mask, was region-selectively exposed to the corona by scanning the electrode tip of the corona generator along the open parts of the mask. Thus, the corona-exposed regions of the paper surface resumed their native hydrophilicity while the masked regions remained highly hydrophobic. The effect of corona treatment time on the paper's hydrophilic property was investigated. Colorimetric assays of nitrite in saliva samples were demonstrated with the developed mPADs. A single-use 'on' valve based on wettability-switching was developed in the mPADs. Fluid control was realized via on-site corona discharge targeted at a hydrophobic barrier design as the 'on' valve.
机译:该工作介绍了一种用于制造基于微流体纸的分析装置(MU焊盘)的容易方法,以及用便携式手持电晕发生器制造基于微流体纸的分析装置(MU垫)。首先,通过将八氯丙基三氯硅烷(OTS)联合到纸纤维素来疏水化滤纸。然后,通过扫描沿着掩模的开口部分扫描电晕发生器的电极尖端,覆盖用钢印塑料掩模覆盖的OTS涂布纸。因此,纸张表面的电晕暴露区域恢复了它们的天然亲水性,而掩蔽区域保持高度疏水性。研究了Corona治疗时间对纸张亲水性的影响。唾液样品中亚硝酸盐的比色测定用发达的MPAD证明。基于润湿性切换的一次使用“ON”阀门在MPAD中开发。通过在疏水性屏障设计中的现场电晕放电实现流体控制作为“ON”阀门。

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  • 来源
    《RSC Advances》 |2016年第4期|共7页
  • 作者单位

    Zhejiang Univ Dept Chem Inst Microanalyt Syst Hangzhou 310058 Zhejiang Peoples R China;

    Chinese Acad Agr Sci Tea Res Inst Hangzhou 310008 Zhejiang Peoples R China;

    Zhejiang Univ Dept Chem Inst Microanalyt Syst Hangzhou 310058 Zhejiang Peoples R China;

    Zhejiang Univ Dept Chem Inst Microanalyt Syst Hangzhou 310058 Zhejiang Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

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