Synthesis And Studies Of Antimicrobial Activity Of Lanceolatin B

摘要

Phytochemical studies of Pongamia pinnata showed an abundance of [2",3":7,8]furanoflavone (lanceolatin B).Now,it has been synthesized from p-resacetophenone via chalcone precursor followed by the treatment of DMSO/I_2,diphenyl sulphide and DDQ,respectively.The antibacterial activity of [2",3":7,8]furanoflavone and its corresponding chalcone were tested by the disc diffusion method for antibacterial effects against Shigella dysenteriae,Salmonella typhi,Streptococcus-beta-haemolyticits and Staphylococcus aureiis.