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首页> 外文期刊>Bioelectrochemistry >Non-thermal effects of continuous 2.45 GHz microwaves on Fas-induced apoptosis in human Jurkat T-cell line
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Non-thermal effects of continuous 2.45 GHz microwaves on Fas-induced apoptosis in human Jurkat T-cell line

机译:连续2.45 GHz微波对Fas诱导的Jurkat T细胞系凋亡的非热效应

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摘要

Non-thermal effects of microwaves(MWs) are one of the main issues studied for revising standards. The effects of MW exposure on apoptosis at non-thermal level (48 h, 2.45 GHz, 5 mW/cm~2) have been studied. Results obtained assess non-thermal MW effects on Fas, but neither on butyrate- nor on ceramide-induced apoptosis in human Jurkat T-cell line. These data show that MW interacts either with Fas pathway between receptor and caspase-3 activation or on membrane proteins (i.e. Fas receptor or neurosphyngomyelinase).
机译:微波的非热效应是修订标准研究的主要问题之一。研究了微波暴露在非热水平(48 h,2.45 GHz,5 mW / cm〜2)下对细胞凋亡的影响。获得的结果评估了非热MW对Fas的影响,但对丁酸或神经酰胺诱导的人Jurkat T细胞系细胞凋亡均无影响。这些数据表明,MW与受体和caspase-3活化之间的Fas途径相互作用或在膜蛋白(即Fas受体或神经鞘磷脂酶)上相互作用。

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