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A case report of recurrent gastric cancer in which combination chemotherapy with paclitaxel and 5-fluorouracil made for successful biliary stenting and improvement in QOL

机译:一种复发性胃癌的病例报告,其中紫杉醇和5-氟尿嘧啶组合化疗对柔软的成功胆汁支出和改善

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摘要

The patient was a 49-year-old female who had undergone a total gastrectomy for gastric cancer on March 9 2001. Pathological diagnosis revealed sig, T 3 (SE), N 2, H 0, P 1, CY 0, M 0, Stage IV, and the curability was C. 5' DFUR 800 mg/day was administered as adjuvant chemotherapy. CDDP 10 mg/body/week intraperitoneally and 5-FU 500 mg/body/week were added. Retention of ascites, peritoneal dissemination, obstructive jaundice and right hydronephrosis appeared in June, 2003, and we started combination chemotherapy with paclitaxel and 5-fluorouracil. 5-fluorouracil (600 mg/m2/day) was infused continuously for 120-hours (days 1-5), and paclitaxel (80 mg/m2) was infused on days 8, 15, and 22 on an outpatient basis. Ascites and peritoneal dissemination had disappeared, and swollen lymph nodes were reduced after 2 courses of the chemotherapy. Furthermore, billiary stenting was performed and a PTCD tube could be removed after 4 courses. No serious adverse effect was observed, and the patient maintained good QOLthrough this treatment.
机译:患者是一名49岁女性,2001年3月9日经历了胃癌的总胃癌。病理诊断显示SIG,T 3(SE),N 2,H 0,P 1,CY 0,M 0,阶段IV,可固化性为C. 5'DFUR 800mg /天作为佐剂化疗给药。加入CDDP 10mg /身体/周腹腔内和5-FU 500 mg /体/周。 2003年6月出现了腹水,腹膜传播,阻塞性黄疸和右肾内肾后膜,我们开始将化疗与紫杉醇和5-氟尿嘧啶组合。 5-氟尿嘧啶(600mg / m2 /天)连续注入120小时(第1-5-5天),并且在门诊基础上,紫杉醇(80mg / m 2)注入了第8天,15天和22天。腹水和腹膜传播消失,在化疗2次疗程后,淋巴结肿大。此外,进行楼支架,在4个课程后可以除去PTCD管。没有观察到严重的不良反应,患者保持这种治疗的良好伤口。

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