Allogeneic Stem-Cell Transplantation in Patients With NPM1-Mutated Acute Myeloid Leukemia: Results From a Prospective Donor Versus No-Donor Analysis of Patients After Upfront HLA Typing Within the SAL-AML 2003 Trial

Roellig Christoph; Bornhaeuser Martin; Kramer Michael; Thiede Christian; Ho Anthony D.; Kraemer Alwin; Schaefer-Eckart Kerstin; Wandt Hannes; Haenel Mathias; Einsele Hermann; Aulitzky Walter E.; Schmitz Norbert; Berdel Wolfgang E.; Stelljes Matthias; Mueller-Tidow Carsten; Krug Utz; Platzbecker Uwe; Wermke Martin; Baldus Claudia D.; Krause Stefan W.; Stoelzel Friedrich; von Bonin Malte; Schaich Markus; Serve Hubert; Schetelig Johannes; Ehninger Gerhard

首页> 外文期刊>Journal of Clinical Oncology >Allogeneic Stem-Cell Transplantation in Patients With NPM1-Mutated Acute Myeloid Leukemia: Results From a Prospective Donor Versus No-Donor Analysis of Patients After Upfront HLA Typing Within the SAL-AML 2003 Trial

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Allogeneic Stem-Cell Transplantation in Patients With NPM1-Mutated Acute Myeloid Leukemia: Results From a Prospective Donor Versus No-Donor Analysis of Patients After Upfront HLA Typing Within the SAL-AML 2003 Trial

机译：NPM1突变急性髓性白血病患者的同种异体干细胞移植：前瞻性供体与患者的未经供体分析在萨尔-AML 2003试验中的初期HLA后的患者患者的结果

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Purpose The presence of a mutated nucleophosmin-1 gene (NPM1(mut)) in acute myeloid leukemia (AML) is associated with a favorable prognosis. To assess the predictive value with regard to allogeneic stem-cell transplantation (SCT), we compared the clinical course of patients with NPM1(mut) AML eligible for allogeneic SCT in a donor versus no-donor analysis.

机译：目的，在急性髓性白血病（AML）中存在突变的核磷素-1基因（NPM1（MUT））与良好的预后有关。为了评估同种异体干细胞移植（SCT）的预测值，我们将患有NPM1（MUT）AML患者的临床进入患者的临床进入患者与捐赠者分析相反。

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来源
《Journal of Clinical Oncology》 |2015年第5期|共8页
作者
Roellig Christoph; Bornhaeuser Martin; Kramer Michael; Thiede Christian; Ho Anthony D.; Kraemer Alwin; Schaefer-Eckart Kerstin; Wandt Hannes; Haenel Mathias; Einsele Hermann; Aulitzky Walter E.; Schmitz Norbert; Berdel Wolfgang E.; Stelljes Matthias; Mueller-Tidow Carsten; Krug Utz; Platzbecker Uwe; Wermke Martin; Baldus Claudia D.; Krause Stefan W.; Stoelzel Friedrich; von Bonin Malte; Schaich Markus; Serve Hubert; Schetelig Johannes; Ehninger Gerhard;
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作者单位

Tech Univ Dresden Med Klin &

Poliklin 1 Univ Klinikum D-01062 Dresden Germany;

Tech Univ Dresden Med Klin &

Poliklin 1 Univ Klinikum D-01062 Dresden Germany;

Tech Univ Dresden Med Klin &

Poliklin 1 Univ Klinikum D-01062 Dresden Germany;

Tech Univ Dresden Med Klin &

Poliklin 1 Univ Klinikum D-01062 Dresden Germany;

Med Univ Klin Abt Innere Med 5 Heidelberg Germany;

Med Univ Klin Abt Innere Med 5 Heidelberg Germany;

Klinikum Nurnberg Med Klin 5 Nurnberg Germany;

Klinikum Nurnberg Med Klin 5 Nurnberg Germany;

Klinikum Chemnitz Klin Innere Med 3 Chemnitz Germany;

Univ Klinikum Wurzburg Med Klin &

Poliklin 2 Wurzburg Germany;

Robert Bosch Krankenhaus Stuttgart Germany;

ASKLEPIOS Klin St Georg Abt Hamatol Onkol &

Stammzelltransplantat Hamburg Germany;

Univ Klinikum Munster Med Klin A Munster Germany;

Univ Klinikum Munster Med Klin A Munster Germany;

Univ Klinikum Halle Univ Klin &

Poliklin Innere Med 4 Halle Saale Germany;

Univ Klinikum Munster Med Klin A Munster Germany;

Tech Univ Dresden Med Klin &

Poliklin 1 Univ Klinikum D-01062 Dresden Germany;

Tech Univ Dresden Med Klin &

Poliklin 1 Univ Klinikum D-01062 Dresden Germany;

Charite Med Klin 3 Charite Ctr 14 D-13353 Berlin Germany;

Univ Klinikum Erlangen Med Klin 5 Erlangen Germany;

Tech Univ Dresden Med Klin &

Poliklin 1 Univ Klinikum D-01062 Dresden Germany;

Tech Univ Dresden Med Klin &

Poliklin 1 Univ Klinikum D-01062 Dresden Germany;

Tech Univ Dresden Med Klin &

Poliklin 1 Univ Klinikum D-01062 Dresden Germany;

Univ Frankfurt Klinikum Med Klin 2 Frankfurt Germany;

Tech Univ Dresden Med Klin &

Poliklin 1 Univ Klinikum D-01062 Dresden Germany;

Tech Univ Dresden Med Klin &

Poliklin 1 Univ Klinikum D-01062 Dresden Germany;

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1. Allogeneic Stem-Cell Transplantation in Patients With NPM1-Mutated Acute Myeloid Leukemia: Results From a Prospective Donor Versus No-Donor Analysis of Patients After Upfront HLA Typing Within the SAL-AML 2003 Trial (vol 33, pg 403, 2015) [J] . Roellig C., Bornhaeuser M., Kramer M. Journal of Clinical Oncology . 2015,第13期

机译：NPM1突变的急性髓性白血病患者的同种异体干细胞移植：在SAL-AML 2003试验中进行前期HLA键入后，前瞻性供体与无供体分析的患者结果（第33卷，第403页，2015年）
2. Allogeneic Stem-Cell Transplantation in Patients With NPM1-Mutated Acute Myeloid Leukemia: Results From a Prospective Donor Versus No-Donor Analysis of Patients After Upfront HLA Typing Within the SAL-AML 2003 Trial [J] . Roellig Christoph, Bornhaeuser Martin, Kramer Michael, Journal of Clinical Oncology . 2015,第5期

机译：NPM1突变的急性髓性白血病患者的同种异体干细胞移植：在SAL-AML 2003试验中预先进行HLA分型后，前瞻性捐赠者与无捐赠者分析的结果
3. Allogeneic Stem-Cell Transplantation in Patients With NPM1-Mutated Acute Myeloid Leukemia: Results From a Prospective Donor Versus No-Donor Analysis of Patients After Upfront HLA Typing Within the SAL-AML 2003 Trial [J] . Roellig Christoph, Bornhaeuser Martin, Kramer Michael, Journal of Clinical Oncology . 2015,第5期

机译：NPM1突变急性髓性白血病患者的同种异体干细胞移植：前瞻性供体与患者的未经供体分析在萨尔-AML 2003试验中的初期HLA后的患者患者的结果
4. Computationally derived cytological image markers for predicting risk of relapse in acute myeloid leukemia patients following bone marrow transplantation [C] . Sara ArabYarmohammadi, Zelin Zhang, Patrick Leo, Conference on Medical Imaging: Digital Pathology . 2020

机译：计算源自骨髓移植后急性髓性白血病患者复发风险的细胞学图像标志物
5. Genetic Associations in Acute Leukemia Patients After Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation [D] . Rizvi, Abbas A. 2019

机译：匹配的无关供体同种异体造血干细胞移植后急性白血病患者的遗传协会。
6. Post-transplant cyclophosphamide versus antithymocyte globulin in patients with acute myeloid leukemia in first complete remission undergoing allogeneic stem cell transplantation from 10/10 HLA-matched unrelated donors [O] . Eolia Brissot, Myriam Labopin, Ian Moiseev, 2020

机译：移植后环磷酰胺与急性髓性白血病患者的患者第一次完全缓解患者的患者从10/10 HLA匹配的无关捐赠者进行同种异体干细胞移植
7. Myeloablative allogeneic versus autologous stem cell transplantation in adult patients with acute lymphoblastic leukemia in first remission: a prospective sibling donor versus no-donor comparison [O] . Cornelissen Jan J, van der Holt Bronno, Verhoef Gregor, 2009

机译：成年急性淋巴细胞白血病初次缓解的成年患者异体异体异体移植与自体干细胞移植：前体同胞供体与非供体的比较

Allogeneic Stem-Cell Transplantation in Patients With NPM1-Mutated Acute Myeloid Leukemia: Results From a Prospective Donor Versus No-Donor Analysis of Patients After Upfront HLA Typing Within the SAL-AML 2003 Trial

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