Comment on 'Solid-Liquid Phase Equilibrium and Thermodynamic Properties of Olaparib in Selected Organic Solvents and (Tetrahydrofuran plus MTBE, Acetonitrile plus Isopropyl Alcohol) Binary Solvent Mixtures'

摘要

Several mathematical errors in the published paper by Zhao and co-workers are identified. The errors pertain to the calculated equation coefficients for the polynomial version of the combined nearly ideal binary solvent (CNIBS)/Redich-Kister and for the Combined Jouyban-Acree-van't Hoff equation. In the case of the CNIBS/Redlich Kister equation the authors' tabulated equation coefficients give 100 times the mole fraction solubility of olaparib, and not the mole fraction solubility as the authors' equation implies.