Association of Aspirin and NSAID Use With Risk of Colorectal Cancer According to Genetic Variants

Nan Hongmei; Hutter Carolyn M.; Lin Yi; Jacobs Eric J.; Ulrich Cornelia M.; White Emily; Baron John A.; Berndt Sonja I.; Brenner Hermann; Butterbach Katja; Caan Bette J.; Campbell Peter T.; Carlson Christopher S.; Casey Graham; Chang-Claude Jenny; Chanock Stephen J.; Cotterchio Michelle; Duggan David; Figueiredo Jane C.; Fuchs Charles S.; Giovannucci Edward L.; Gong Jian; Haile Robert W.; Harrison Tabitha A.; Hayes Richard B.; Hoffmeister Michael; Hopper John L.; Hudson Thomas J.; Jenkins Mark A.; Jiao Shuo; Lindor Noralane M.; Lemire Mathieu; Le Marchand Loic; Newcomb Polly A.; Ogino Shuji; Pflugeisen Bethann M.; Potter John D.; Qu Conghui; Rosse Stephanie A.; Rudolph Anja; Schoen Robert E.; Schumacher Fredrick R.; Seminara Daniela; Slattery Martha L.; Thibodeau Stephen N.; Thomas Fridtjof; Thornquist Mark; Warnick Greg S.; Zanke Brent W.; Gauderman W. James; Peters Ulrike; Hsu Li; Chan Andrew T.

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Association of Aspirin and NSAID Use With Risk of Colorectal Cancer According to Genetic Variants

机译：阿司匹林和NSAID与遗传变异癌症风险的关联

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IMPORTANCE Use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with lower risk of colorectal cancer.

机译：阿司匹林和其他非甾体抗炎药（NSAID）的重要性使用与较低的结肠直肠癌风险有关。

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来源
《JAMA: the Journal of the American Medical Association》 |2015年第11期|共10页
作者
Nan Hongmei; Hutter Carolyn M.; Lin Yi; Jacobs Eric J.; Ulrich Cornelia M.; White Emily; Baron John A.; Berndt Sonja I.; Brenner Hermann; Butterbach Katja; Caan Bette J.; Campbell Peter T.; Carlson Christopher S.; Casey Graham; Chang-Claude Jenny; Chanock Stephen J.; Cotterchio Michelle; Duggan David; Figueiredo Jane C.; Fuchs Charles S.; Giovannucci Edward L.; Gong Jian; Haile Robert W.; Harrison Tabitha A.; Hayes Richard B.; Hoffmeister Michael; Hopper John L.; Hudson Thomas J.; Jenkins Mark A.; Jiao Shuo; Lindor Noralane M.; Lemire Mathieu; Le Marchand Loic; Newcomb Polly A.; Ogino Shuji; Pflugeisen Bethann M.; Potter John D.; Qu Conghui; Rosse Stephanie A.; Rudolph Anja; Schoen Robert E.; Schumacher Fredrick R.; Seminara Daniela; Slattery Martha L.; Thibodeau Stephen N.; Thomas Fridtjof; Thornquist Mark; Warnick Greg S.; Zanke Brent W.; Gauderman W. James; Peters Ulrike; Hsu Li; Chan Andrew T.;
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作者单位

Indiana Univ Richard M Fairbanks Sch Publ Hlth Dept Epidemiol Indianapolis IN 46204 USA;

NHGRI NIH Bethesda MD 20892 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Amer Canc Soc Epidemiol Res Program Atlanta GA 30329 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Univ N Carolina Sch Med Div Gastroenterol &

Hepatol Chapel Hill NC USA;

NCI Div Canc Epidemiol &

Genet NIH Bethesda MD 20892 USA;

German Canc Res Ctr Div Clin Epidemiol &

Aging Res Heidelberg Germany;

German Canc Res Ctr Div Clin Epidemiol &

Aging Res Heidelberg Germany;

Kaiser Permanente Med Care Program No Calif Div Res Oakland CA USA;

Amer Canc Soc Epidemiol Res Program Atlanta GA 30329 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Univ So Calif Keck Sch Med Dept Prevent Med Los Angeles CA 90033 USA;

German Canc Res Ctr Div Canc Epidemiol Heidelberg Germany;

NCI Div Canc Epidemiol &

Genet NIH Bethesda MD 20892 USA;

Canc Care Ontario Prevent &

Canc Control Toronto ON Canada;

Translat Genom Res Inst TGen Genet Basis Human Dis Div Phoenix AZ USA;

Univ So Calif Keck Sch Med Dept Prevent Med Los Angeles CA 90033 USA;

Dana Farber Canc Inst Dept Med Oncol Boston MA 02115 USA;

Harvard Univ Brigham &

Womens Hosp Sch Med Dept Med Channing Div Network Med Boston MA 02115;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Univ So Calif Keck Sch Med Dept Prevent Med Los Angeles CA 90033 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

NYU Sch Med Dept Populat Hlth Div Epidemiol New York NY USA;

German Canc Res Ctr Div Clin Epidemiol &

Aging Res Heidelberg Germany;

Univ Melbourne Melbourne Sch Populat Hlth Melbourne Vic 3010 Australia;

Univ Toronto Dept Med Biophys Toronto ON Canada;

Univ Melbourne Melbourne Sch Populat Hlth Melbourne Vic 3010 Australia;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Mayo Clin Dept Hlth Sci Res Scottsdale AZ USA;

Ontario Inst Canc Res Toronto ON Canada;

Univ Hawaii Ctr Canc Program Epidemiol Honolulu HI 96822 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Dana Farber Canc Inst Dept Med Oncol Boston MA 02115 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

German Canc Res Ctr Div Canc Epidemiol Heidelberg Germany;

Univ Pittsburgh Med Ctr Dept Med &

Epidemiol Pittsburgh PA USA;

Univ So Calif Keck Sch Med Dept Prevent Med Los Angeles CA 90033 USA;

NHGRI NIH Bethesda MD 20892 USA;

Univ Utah Hlth Sci Ctr Dept Internal Med Salt Lake City UT USA;

Mayo Clin Dept Lab Med &

Pathol Rochester MN USA;

Univ Tennessee Ctr Hlth Sci Dept Prevent Med Div Biostat &

Epidemiol Memphis TN 38163 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Ottawa Hosp Res Inst Clin Epidemiol Program Ottawa ON Canada;

Univ So Calif Keck Sch Med Dept Prevent Med Los Angeles CA 90033 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Seattle WA 98104 USA;

Harvard Univ Brigham &

Womens Hosp Sch Med Dept Med Channing Div Network Med Boston MA 02115;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
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入库时间 2022-08-19 19:21:17

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专利

1. Association of Aspirin and NSAID Use With Risk of Colorectal Cancer According to Genetic Variants [J] . Nan Hongmei, Hutter Carolyn M., Lin Yi, JAMA: the Journal of the American Medical Association . 2015,第11期

机译：阿司匹林和NSAID与遗传变异癌症风险的关联
2. Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: Colon cancer family registry [J] . SchererD., KoeplL.M., PooleE.M., Genes, Chromosomes and Cancer . 2014,第7期

机译：UGT基因的遗传变异改变了NSAIDs与大肠癌风险的关联：结肠癌家族注册
3. The association of a genetic variant in CDKN2A/B gene and the risk of colorectal cancer [J] . Farzad Rahmani, Amir Avan, Forouzan Amerizadeh, EXCLI Journal . 2020,第3期

机译：CDKN2A / B基因遗传变异的关联及结直肠癌的风险
4. Association of selenoprotein and selenium pathway genetic variations with colorectal cancer risk and interaction with selenium status [C] . D.J. Hughes, V. Fedirko, J.S. Jones, International Conference on Selenium in the Environment and Human Health . 2016

机译：硒蛋白和硒途径遗传变异与结肠直肠癌风险的变异和与硒状况的相互作用
5. Prostate cancer risk and inflammation: Association with aspirin and other NSAID use & selected inflammation pathway-related gene polymorphisms. [D] . Salinas, Claudia A. 2009

机译：前列腺癌的风险和炎症：与阿司匹林和其他NSAID的使用以及选定的炎症途径相关的基因多态性相关。
6. Genetic Variation in UGT Genes Modify the Associations of NSAIDs with Risk of Colorectal Cancer: Colon Cancer Family Registry [O] . Dominique Scherer, Lisel M Koepl, Elizabeth M Poole, -1

机译：UGT基因的遗传变异修改NSAIDs与大肠癌风险的关联：结肠癌家庭注册
7. Association of Aspirin and NSAID Use With Risk of Colorectal Cancer According to Genetic Variants [O] . orcid:0000-0002-6129-1572, orcid:0000-0002-0918-661X, orcid:0000-0002-8307-3197, 2015

机译：根据遗传变异，阿司匹林和NsaID与结直肠癌风险的关联

Association of Aspirin and NSAID Use With Risk of Colorectal Cancer According to Genetic Variants

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