A mouse model with age-dependent immune response and immune-tolerance for HBV infection

Yi Xuerui; Yuan Youcheng; Li Na; Yi Lu; Wang Cuiling; Qi Ying; Gong Liang; Liu Guangze; Kong Xiangping

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A mouse model with age-dependent immune response and immune-tolerance for HBV infection

机译：具有年龄依赖性免疫应答和HBV感染的免疫应答的小鼠模型

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Background: Viral clearance of human HBV infection largely depends on the age of exposure. Thus, a mouse model with age-dependent immune response and immune-tolerance for HBV infection was established.

机译：背景：人HBV感染的病毒清除在很大程度上取决于暴露的年龄。因此，建立了具有年龄依赖性免疫应答和用于HBV感染的免疫应答和免疫耐受的小鼠模型。

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来源
《Vaccine》 |2018年第6期|共8页
作者
Yi Xuerui; Yuan Youcheng; Li Na; Yi Lu; Wang Cuiling; Qi Ying; Gong Liang; Liu Guangze; Kong Xiangping;
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作者单位

458th Hosp Guangzhou Liver Dis Res Ctr 801 Dongfeng East Rd Guangzhou 510600 Guangdong Peoples R China;

458th Hosp Guangzhou Liver Dis Res Ctr 801 Dongfeng East Rd Guangzhou 510600 Guangdong Peoples R China;

458th Hosp Guangzhou Liver Dis Res Ctr 801 Dongfeng East Rd Guangzhou 510600 Guangdong Peoples R China;

458th Hosp Guangzhou Liver Dis Res Ctr 801 Dongfeng East Rd Guangzhou 510600 Guangdong Peoples R China;

458th Hosp Guangzhou Liver Dis Res Ctr 801 Dongfeng East Rd Guangzhou 510600 Guangdong Peoples R China;

458th Hosp Guangzhou Liver Dis Res Ctr 801 Dongfeng East Rd Guangzhou 510600 Guangdong Peoples R China;

458th Hosp Guangzhou Liver Dis Res Ctr 801 Dongfeng East Rd Guangzhou 510600 Guangdong Peoples R China;

458th Hosp Guangzhou Liver Dis Res Ctr 801 Dongfeng East Rd Guangzhou 510600 Guangdong Peoples R China;

458th Hosp Guangzhou Liver Dis Res Ctr 801 Dongfeng East Rd Guangzhou 510600 Guangdong Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
Hepatitis B virus; Mouse model; Age-dependent; Immune tolerance; GS-9620; Functional cure;

机译：乙型肝炎病毒;小鼠模型;年龄依赖性;免疫耐受性;GS-9620;功能性固化;

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专利

1. A mouse model with age-dependent immune response and immune-tolerance for HBV infection [J] . Yi Xuerui, Yuan Youcheng, Li Na, Vaccine . 2018,第6期

机译：具有年龄依赖性免疫应答和HBV感染的免疫应答的小鼠模型
2. Effect of trichinella spiralis infection on the immune response to HBV vaccine in a mouse model [J] . GuanF., HouX., NieG., Foodborne pathogens and disease . 2013,第10期

机译：旋毛虫旋毛虫感染对小鼠模型对HBV疫苗免疫反应的影响
3. Immunity to Hepatitis B Virus (HBV) Infection Two Decades after Implementation of Universal Infant HBV Vaccination: Association of Detectable Residual Antibodies and Response to a Single HBV Challenge Dose [J] . Philip R. Spradling, Jian Xing, Roxanne Williams, Clinical and vaccine immunology: CVI . 2013,第4期

机译：实施通用婴儿HBV疫苗后两个十年对乙型肝炎病毒（HBV）感染的免疫力：可检测的残留抗体和对单个HBV挑战剂量的反应的关联
4. Modeling the Immune Response to HBV Infection [C] . Long, Changjiang, Qi, Huan, Qu, Anlian, International Conference on Computational Intelligence and Software Engineering;CiSE 2009 . 2009

机译：模拟对HBV感染的免疫反应
5. Examining immune responses in a mouse model of Salmonella infection. [D] . Griffin, Amanda Jill. 2010

机译：在沙门氏菌感染的小鼠模型中检查免疫反应。
6. Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection [O] . Valeria Fumagalli, Pietro Di Lucia, Valentina Venzin, 2020

机译：血清HBsAg间隙对HBV感染小鼠模型中的CD8 + T细胞应答具有最小的影响
7. Immune response during hepatitis B virus infection and reconstitution of HBV-specific immunity using T cells redirected against HBV [O] . Koh Sarene 2013

机译：乙型肝炎病毒感染期间的免疫应答和使用针对HBV重定向的T细胞重建HBV特异性免疫

A mouse model with age-dependent immune response and immune-tolerance for HBV infection

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