Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

Graham Mark J.; Lee Richard G.; Brandt Teresa A.; Tai Li-jung; Fu Wuxia; Peralta Raechel; Yu Rosie; Hurh Eunju; Paz Erika; McEvoy Bradley W.; Baker Brenda F.; Pham Nguyen C.; Digenio Andres; Hughes Steven G.; Geary Richard S.; Witztum Joseph L.; Crooke Rosanne M.; Tsimikas Sotirios

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Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

机译：Angptl3反义寡核苷酸的心血管和代谢效应

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来源
《The New England journal of medicine》 |2017年第3期|共11页
作者
Graham Mark J.; Lee Richard G.; Brandt Teresa A.; Tai Li-jung; Fu Wuxia; Peralta Raechel; Yu Rosie; Hurh Eunju; Paz Erika; McEvoy Bradley W.; Baker Brenda F.; Pham Nguyen C.; Digenio Andres; Hughes Steven G.; Geary Richard S.; Witztum Joseph L.; Crooke Rosanne M.; Tsimikas Sotirios;
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Ionis Pharmaceut Carlsbad CA USA;

Ionis Pharmaceut Carlsbad CA USA;

Ionis Pharmaceut Carlsbad CA USA;

Ionis Pharmaceut Carlsbad CA USA;

Ionis Pharmaceut Carlsbad CA USA;

Ionis Pharmaceut Carlsbad CA USA;

Ionis Pharmaceut Carlsbad CA USA;

Akcea Therapeut Cambridge MA USA;

Ionis Pharmaceut Carlsbad CA USA;

Ionis Pharmaceut Carlsbad CA USA;

Ionis Pharmaceut Carlsbad CA USA;

Ionis Pharmaceut Carlsbad CA USA;

Akcea Therapeut Cambridge MA USA;

Ionis Pharmaceut Carlsbad CA USA;

Ionis Pharmaceut Carlsbad CA USA;

Univ Calif San Diego La Jolla CA 92093 USA;

Ionis Pharmaceut Carlsbad CA USA;

Ionis Pharmaceut Carlsbad CA USA;

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正文语种 eng
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专利

1. Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides [J] . Graham Mark J., Lee Richard G., Brandt Teresa A., The New England journal of medicine . 2017,第3期

机译：Angptl3反义寡核苷酸的心血管和代谢效应
2. Antisense oligonucleotides on neurobehavior, respiratory, and cardiovascular function, and hERG channel current studies [J] . Tae-Won Kim, Ki-Suk Kim, Joung-Wook Seo, Journal of Pharmacological and Toxicological Methods . 2014,第1期

机译：关于神经行为，呼吸和心血管功能以及hERG通道电流研究的反义寡核苷酸
3. Antisense oligonucleotides as a powerful molecular strategy for gene therapy in cardiovascular diseases. [J] . Tomita N, Morishita R Current pharmaceutical design . 2004,第7期

机译：反义寡核苷酸是心血管疾病基因治疗的强大分子策略。
4. Effects of insonated phospholipids-based microbubbles on the transfection of Antisense Oligonucleotides [C] . Xiaobing ZHANG Novel Drug Delivery Systems: Research and Application . 2007

机译：声波磷脂基微泡对反义寡核苷酸转染的影响
5. Interplay of polymer and oligonucleotide properties in the nature of antisense effects. [D] . Sundaram, Sumati. 2008

机译：聚合物和寡核苷酸性质的相互作用具有反义作用的性质。
6. Antisense oligonucleotide‐mediated knockdown of Mpzl3 attenuates the negative metabolic effects of diet‐induced obesity in mice [O] . Beth L. Worley, Thomas Auen, Amy C. Arnold, 2021

机译：反义寡核苷酸介导的MPZL3的敲敲衰减饮食诱导的小鼠肥胖的负代谢效应
7. Antisense oligonucleotide‐mediated knockdown of Mpzl3 attenuates the negative metabolic effects of diet‐induced obesity in mice [O] . Beth L. Worley, Thomas Auen, Amy C. Arnold, 2021

机译：反义寡核苷酸介导的MPZL3的敲敲衰减饮食诱导的小鼠肥胖的负代谢效应

Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

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