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首页> 外文期刊>The Journal of Thoracic and Cardiovascular Surgery >Incremental risk of the Cox-maze IV procedure for patients with atrial fibrillation undergoing mitral valve surgery
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Incremental risk of the Cox-maze IV procedure for patients with atrial fibrillation undergoing mitral valve surgery

机译:心房颤动患者患有二尖瓣手术的患者的Cox-Maze IV程序的增量风险

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摘要

Objective More than 50% of atrial fibrillation surgery occurs in the setting of mitral valve surgery. Despite this, no risk models have been validated for concomitant arrhythmia surgery. The purpose of the present study was to quantify the additional risk of performing the Cox-maze IV procedure for patients undergoing mitral valve surgery. Methods From January 2002 to June 2011, 213 patients with mitral valve disease and preoperative atrial fibrillation underwent mitral valve surgery only (n = 109) or in conjunction with a Cox-maze IV procedure (n = 104). The operative mortality for the mitral valve procedure alone was predicted for each group using the Society of Thoracic Surgeons perioperative risk calculator. The risk attributed to the added Cox-maze IV procedure was calculated by comparing the predicted mortality rate of an isolated mitral valve procedure and the actual mortality rate of mitral valve surgery with a concomitant Cox-maze IV procedure. Results For patients not undergoing a Cox-maze IV procedure, the predicted and actual postoperative mortality rate was 5.5% and 4.6% (5 of 109), respectively. For patients receiving mitral valve surgery and a concomitant Cox-maze IV, the predicted and actual postoperative mortality of the mitral valve procedure was 2.5% and 2.9% (3 of 104), respectively, and not significantly different. Patients not offered a Cox-maze IV procedure had significantly more serious comorbidities. Conclusions For patients with atrial fibrillation and mitral valve disease undergoing mitral valve surgery, the decision to offer a concomitant Cox-maze IV procedure will be influenced by the underlying comorbid conditions. Nonetheless, in selected lower risk patients, the addition of a Cox-maze IV procedure did not significantly affect the procedural mortality.
机译:客观心房颤动手术的50%以上在二尖瓣手术的设定发生。尽管这样,没有风险模型已被验证为伴心律不齐手术。本研究的目的是量化执行对接受二尖瓣手术患者的Cox-IV迷宫手术的额外风险。方法自2002年1月至2011年6月,213名患者二尖瓣病变及术前心房颤动后行二尖瓣手术只(N = 109)或连同考克斯迷宫IV过程(N = 104)。对于单独的二尖瓣过程手术死亡率预测使用胸外科医师围手术风险计算器学会每个组。归因于加入的Cox-IV迷宫程序的风险通过比较预测的死亡率的分离的二尖瓣程序和实际死亡率二尖瓣手术的与并用的Cox-IV迷宫程序计算。结果对于患者不经历的Cox-IV迷宫程序,预测的和实际的术后死亡率分别为5.5%和4.6%(109 5),。用于接收二尖瓣手术和伴随的Cox-IV迷宫患者,二尖瓣过程的预测值和实际术后死亡率分别为2.5%和2.9%(104 3),而不是显著不同。患者不要提供了考克斯迷宫IV程序有显著更严重的合并症。结论对于房颤患者和二尖瓣病变接受二尖瓣手术,提供一个伴随考克斯迷宫IV程序的决定将通过底层合并症的影响。然而,在选择风险较低的患者,增加了一个考克斯迷宫IV程序并没有显著影响程序的死亡率。

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  • 作者单位

    Division of Cardiothoracic Surgery Washington University School of Medicine Barnes-Jewish;

    Division of Cardiothoracic Surgery Washington University School of Medicine Barnes-Jewish;

    Division of Cardiology Washington University School of Medicine St Louis MO United States;

    Division of Cardiothoracic Surgery Washington University School of Medicine Barnes-Jewish;

    Division of Cardiothoracic Surgery Washington University School of Medicine Barnes-Jewish;

    Division of Cardiothoracic Surgery Washington University School of Medicine Barnes-Jewish;

    Division of Cardiothoracic Surgery Washington University School of Medicine Barnes-Jewish;

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  • 正文语种 eng
  • 中图分类 心脏、血管(循环系)疾病;
  • 关键词

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