Synthesis of Neplanocin A and Its 3′-Epimer via an Intramolecular Baylis?Hillman Reaction

Yun Xuan Tan; Sridhar Santhanakrishnan; Hai Yan Yang; Christina L. L. Chai; Eric Kwok Wai Tam

首页> 外文期刊>The Journal of Organic Chemistry >Synthesis of Neplanocin A and Its 3′-Epimer via an Intramolecular Baylis?Hillman Reaction

【24h】

Synthesis of Neplanocin A and Its 3′-Epimer via an Intramolecular Baylis?Hillman Reaction

机译：通过分子内Baylis合成Neplanocin A及其3'-基皮的α·斯金曼反应

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The key cyclopentenyl intermediate 11b was synthesized in 4 steps from D-ribose in 41% overall yield via an efficient intramolecular Baylis?Hillman reaction. This novel key intermediate can be modified easily and transformed to neplanocin A (1a) and its 3′-epimer (1b).

机译：关键环戊烯基中间体11B通过高效的分子内Baylis（Hillman反应）以41％的总收率在41％的总收率中合成4步。可以容易地修饰该新型键中间体并转化为Neplanocin A（1A）及其3'-基础（1B）。

著录项

来源
《The Journal of Organic Chemistry》 |2014年第17期|共8页
作者
Yun Xuan Tan; Sridhar Santhanakrishnan; Hai Yan Yang; Christina L. L. Chai; Eric Kwok Wai Tam;
展开▼
作者单位

Institute of Chemical &

Engineering Sciences A*STAR (Agency for Science Technology and Research) 8 Biomedical Grove Neuros#07-01 Singapore 13866;

Institute of Chemical &

Engineering Sciences A*STAR (Agency for Science Technology and Research) 8 Biomedical Grove Neuros#07-01 Singapore 13866;

Institute of Chemical &

Engineering Sciences A*STAR (Agency for Science Technology and Research) 8 Biomedical Grove Neuros#07-01 Singapore 13866;

Institute of Chemical &

Engineering Sciences A*STAR (Agency for Science Technology and Research) 8 Biomedical Grove Neuros#07-01 Singapore 13866;

Institute of Chemical &

Engineering Sciences A*STAR (Agency for Science Technology and Research) 8 Biomedical Grove Neuros#07-01 Singapore 13866;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类有机化学;
关键词
Neplanocin; Intramolecular; Reaction;

机译：Neplanocin;骨分子;反应;

相似文献

外文文献
中文文献
专利

1. Synthesis of Neplanocin A and Its 3′-Epimer via an Intramolecular Baylis?Hillman Reaction [J] . Yun Xuan Tan, Sridhar Santhanakrishnan, Hai Yan Yang, The Journal of Organic Chemistry . 2014,第17期

机译：通过分子内Baylis合成Neplanocin A及其3'-基皮的α·斯金曼反应
2. Synthesis of unsaturated seven-membered ring lactams through palladium-catalyzed amination and intramolecular cyclocarbonylation reactions of amines and Baylis-Hillman acetates [J] . Cao H., Vieira T.O., Alper H. Organic letters . 2011,第1期

机译：通过钯和胺与Baylis-Hillman乙酸酯的钯催化胺化和分子内环羰基化反应合成不饱和七元环内酰胺
3. Synthesis of sultam scaffolds via intramolecular oxa-Michael and diastereoselective Baylis-Hillman reactions [J] . Zhou AH, Hanson PR Organic letters . 2008,第14期

机译：通过分子内的oxa-Michael和非对映选择性Baylis-Hillman反应合成sultam支架
4. Intramolecular Morita-Baylis-Hillman Reaction Using Chiral Phosphine Catalysts and the Synthetic Application [C] . Koichi Higashio, Tomonori Misaki, Takashi Sugimura 日本化学会春季年会講演予稿集 . 2018

机译：分子内森氏村 - 山丘 - 山丘山反应使用手性磷酸催化剂和合成施用
5. Harnessing single amino acid catalysis: Development of the enantioselective intramolecular Morita-Baylis-Hillman and Rauhut-Currier reactions and studies toward the synthesis of (+)-Sch 642305 [D] . Aroyan, Carrie Elizabeth 2008

机译：利用单一氨基酸催化：对映选择性分子内Morita-Baylis-Hillman和Rauhut-Currier反应的发展以及对（+）-Sch 642305合成的研究
6. Synthesis of Sultam Scaffolds via Intramolecular Oxa-Michael and Diastereoselective Baylis—Hillman Reactions [O] . Aihua Zhou, Paul R. Hanson -1

机译：通过分子内的Oxa-Michael和非对映选择性Baylis-Hillman反应合成Sultam支架
7. Synthesis of Sultam Scaffolds via Intramolecular Oxa-Michael and Diastereoselective Baylis−Hillman Reactions [O] . Aihua Zhou, Paul R. Hanson 2008

机译：通过分子内的Oxa-Michael和Dia对映选择性Baylis-Hillman反应合成肥皂屑支架

Synthesis of Neplanocin A and Its 3′-Epimer via an Intramolecular Baylis?Hillman Reaction

摘要

著录项

相似文献

相关主题

期刊订阅