Albers-Schbnberg first reported osteopetrosis in 1904 in an adult patient with generalized bone sclerosis and multiple fractures.1 Osteopetrosis is a heterogeneous group of inherited bone remodeling disorders in which there is a defect in bone resorption by osteoclasts. The disease is associated with an increase in skeletal mass due to abnormally dense bone. The decrease in osteo-clastic activity also affects the shape and structure of the bone. Abnormal remodeling of primary woven bone to lamellar bone results in brittle bone that is prone to fracture.
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