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Risk factors associated with revision for prosthetic joint infection following knee replacement: an observational cohort study from England and Wales

机译:膝关节置换术后假体关节感染的危险因素:英格兰和威尔士的观察队列研究

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Background Prosthetic joint infection is a devastating complication of knee replacement. The risk of developing a prosthetic joint infection is affected by patient, surgical, and health-care system factors. Existing evidence is limited by heterogeneity in populations studied, short follow-up, inadequate power, and does not differentiate early prosthetic joint infection, most likely related to the intervention, from late infection, more likely to occur due to haematogenous bacterial spread. We aimed to assess the overall and time-specific associations of these factors with the risk of revision due to prosthetic joint infection following primary knee replacement.
机译:背景技术假体关节感染是膝关节置换造型的破坏性并发症。 发展假性关节感染的风险受患者,手术和保健系统因素的影响。 现有证据受到研究人口的异质性的限制,短暂的随访,力量不足,并且不会区分早期的假期关节感染,最可能与晚期感染有关,从晚期感染,由于血液源细菌扩散,更可能发生。 我们的旨在评估这些因素的总体和时间特异性关联,由于初级膝关节置换后由于假膝关节感染而导致的修订风险。

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  • 来源
    《Nature reviews Cancer》 |2019年第6期|共12页
  • 作者单位

    Univ Bristol Bristol Med Sch Musculoskeletal Res Unit Translat Hlth Sci Bristol Avon England;

    Univ Bristol Bristol Med Sch Musculoskeletal Res Unit Translat Hlth Sci Bristol Avon England;

    Univ Bristol Bristol Med Sch Musculoskeletal Res Unit Translat Hlth Sci Bristol Avon England;

    Univ Bristol Bristol Med Sch Musculoskeletal Res Unit Translat Hlth Sci Bristol Avon England;

    Univ Hosp Coventry &

    Warwickshire NHS Trust Coventry W Midlands England;

    Wrightington Hosp Ctr Hip Surg Wigan England;

    Univ Bristol Bristol Med Sch Musculoskeletal Res Unit Translat Hlth Sci Bristol Avon England;

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  • 正文语种 eng
  • 中图分类 肿瘤学;
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