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A universal parameterized gradient‐based method for photon beam field size determination

机译:基于通用参数化梯度的光子束场大小确定方法

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摘要

Purpose To propose a universal, parameterized gradient‐based method (PGM) for radiation field size determination. Methods The PGM locates the beam profile's edge by parameterizing its penumbra region with a modified sigmoid function where the inflection point can be determined in a closed form. The parametrization was validated with filter‐flattened (FF), flattening‐filter‐free (FFF) and wedged profiles measured on two Elekta linac models (Synergy and Versa HD). Gamma analysis with the delta dose function set to zero was used to quantitatively assess the parameterization accuracy. Field sizes of FF beams were calculated with the PGM and the full width at half maximum (FWHM) methods for comparison. To assess the consistency of the PGM and the FWHM method with geometric scaling across different depths, the calculated field size at a reference depth was scaled to other depths and compared with the field sizes calculated from the measured profiles. The method was also validated against a maximum‐slope method (MSM) with wedge and FFF profiles. We also evaluated the robustness of the three methods with respect to measurement noise, varying scanning step sizes, detector characteristics, and beam energy/modality. Results Small distance‐to‐agreement (0.02?±?0.02?mm) between the measured and parameterized penumbra region was observed for all profiles. The differences between the field sizes calculated with the FWHM method and the PGM were consistent (0.9?±?0.3?mm), with the FWHM method yielding larger values. With geometrical scaling, the PGM and the FWHM method produced maximum differences of 0.26 and 1.16?mm, respectively. For wedge and FFF beams, the mean differences relative to FF fields were 0.15?±?0.09?mm and 0.57?±?0.91?mm for the PGM and the MSM, respectively. The PGM was also found to produce more consistent results than the FWHM method and the MSM when measurement noise, scanning step size, detector characteristics, and beam energy/modality changed. Conclusion The proposed PGM is universally applicable to all beam modalities (FF, wedge and FFF) for accurate field size determination. Compared to the FWHM and the MSM, it is more robust to variations in measurement condition and detection system.
机译:目的提出用于辐射场大小确定的通用,参数化基于梯度的方法(PGM)。方法PGM通过将其PENUMBRA区域参数来定位光束轮廓的边缘,其中可以以封闭形式确定拐点的修改变形函数。在两个Elekta LinaC模型(Synergy和Versa HD)上测量的滤纱(FF),扁平滤网(FF)和无楔形剖面验证了参数化。使用设置为零的Delta剂量函数的Gamma分析用于定量评估参数化精度。使用PGM和半最大(FWHM)方法的PGM计算FF光束的场尺寸以进行比较。为了评估PGM和FWHM方法在不同深度上具有几何缩放的FWHM方法的一致性,参考深度的计算出的字段大小被缩放到其他深度,并与从测量的轮廓计算的场尺寸进行比较。该方法还针对具有楔形和FFF配置文件的最大斜率方法(MSM)验证。我们还评估了三种方法关于测量噪声,改变扫描步长,检测器特性和光束能量/模态的鲁棒性。结果为所有轮廓观察到测量和参数化的PENUMBRA区域之间的小距离距离(0.02?±0.02Ω·mm)。用FWHM方法计算的场尺寸与PGM之间的差异是一致的(0.9?±0.3Ω·0.3毫秒),其FWHM方法产生更大的值。具有几何缩放,PGM和FWHM方法分别产生0.26和1.16Ωmm的最大差异。对于楔形和FFF光束,相对于FF场的平均差异分别为0.15?±0.09Ω·mm和0.57?±0.91Ωmm,分别为MSM和MSM。当测量噪声,扫描步长,检测器特性和光束能量/模态改变时,也发现PGM产生比FWHM方法和MSM更一致的结果。结论所提出的PGM普遍适用于所有光束模态(FF,楔形和FFF),用于精确场尺寸测定。与FWHM和MSM相比,对测量条件和检测系统的变化更加稳健。

著录项

  • 来源
    《Medical Physics》 |2017年第11期|共11页
  • 作者单位

    Department of Radiation OncologyUniversity of Florida College of MedicineGainesville FL 32610‐0385;

    Department of Radiation OncologyUniversity of Florida College of MedicineGainesville FL 32610‐0385;

    Department of Radiation OncologyUniversity of Florida College of MedicineGainesville FL 32610‐0385;

    Department of Radiation OncologyUniversity of Florida College of MedicineGainesville FL 32610‐0385;

    Department of Radiation OncologyUniversity of Florida College of MedicineGainesville FL 32610‐0385;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 基础医学;
  • 关键词

    field size; linac; parameterization; quality assurance;

    机译:字段大小;LINAC;参数化;质量保证;

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