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首页> 外文期刊>Medical Physics >SU‐F‐T‐65: AutomaticTreatment Planning for High‐Dose Rate (HDR) Brachytherapy with a VaginalCylinder Applicator
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SU‐F‐T‐65: AutomaticTreatment Planning for High‐Dose Rate (HDR) Brachytherapy with a VaginalCylinder Applicator

机译:SU-F-T-65:具有阴道晶片涂敷器的高剂量率(HDR)近距离放射治疗的自动训练计划

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Purpose: High dose rate (HDR) brachytherapy treatment planning is conventionally performed in a manual fashion. Yet it is highly desirable to perform computerized automated planning to improve treatment planning efficiency, eliminate human errors, and reduce plan quality variation. The goal of this research is to develop an automatic treatment planning tool for HDR brachytherapy with a cylinder applicator for vaginal cancer. Methods: After inserting the cylinder applicator into the patient, a CT scan was acquired and was loaded to an in‐house developed treatment planning software. The cylinder applicator was automatically segmented using image‐processing techniques. CTV was generated based on user‐specified treatment depth and length. Locations of relevant points (apex point, prescription point, and vaginal surface point), central applicator channel coordinates, and dwell positions were determined according to their geometric relations with the applicator. Dwell time was computed through an inverse optimization process. The planning information was written into DICOM‐RT plan and structure files to transfer the automatically generated plan to a commercial treatment planning system for plan verification and delivery. Results: We have tested the system retrospectively in nine patients treated with vaginal cylinder applicator. These cases were selected with different treatment prescriptions, lengths, depths, and cylinder diameters to represent a large patient population. Our system was able to generate treatment plans for these cases with clinically acceptable quality. Computation time varied from 3–6 min. Conclusion: We have developed a system to perform automated treatment planning for HDR brachytherapy with a cylinder applicator. Such a novel system has greatly improved treatment planning efficiency and reduced plan quality variation. It also served as a testbed to demonstrate the feasibility of automatic HDR treatment planning for more complicated cases.
机译:目的:通常以手动方式进行高剂量率(HDR)近距离治疗计划。然而,非常希望能够进行计算机化的自动规划以改善治疗计划效率,消除人类错误,降低计划质量变化。该研究的目标是开发一种用于HDR近距离放射治疗的自动治疗计划,用气缸涂抹器用于阴道癌。方法:将气缸涂敷器插入患者后,获取CT扫描并加载到内部开发的治疗计划软件。气缸涂抹器使用图像处理技术自动分段。基于用户指定的治疗深度和长度生成CTV。根据与涂抹器的几何关系确定相关点(顶点点,处方点和阴道表面点),中央涂抹器通道坐标和停留位置的位置。停留时间通过逆优化过程计算。计划信息被写入DICOM-RT计划和结构文件,以将自动生成的计划转移到商业处理计划系统,以进行计划核查和交付。结果:我们已经在用阴道缸涂抹器治疗的九个患者中回顾性地测试了系统。用不同的治疗处方,长度,深度和圆柱直径选择这些病例,以代表大患者群体。我们的系统能够以临床可接受的质量为这些案例产生治疗计划。计算时间从3-6分钟变化。结论:我们开发了一种系统,用于用汽缸涂抹器对HDR近距离放射治疗进行自动化处理计划。这种新型系统具有大大提高了治疗计划效率和降低的计划质量变化。它还担任试验台,以证明自动HDR治疗计划的可行性,以获得更复杂的情况。

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