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机译:5-羟基吡啶[2,3- b]吡嗪-6(5h) - 衍生物作为HIV-1逆转录酶相关核糖核酸酶H和整合酶的新型双重抑制剂
Department of Medicinal Chemistry Key Laboratory of Chemical Biology Ministry of Education;
Department of Medicinal Chemistry Key Laboratory of Chemical Biology Ministry of Education;
Department of Medicinal Chemistry Key Laboratory of Chemical Biology Ministry of Education;
Department of Medicinal Chemistry Key Laboratory of Chemical Biology Ministry of Education;
Department of Medicinal Chemistry Key Laboratory of Chemical Biology Ministry of Education;
Department of Medicinal Chemistry Key Laboratory of Chemical Biology Ministry of Education;
Department of Medicinal Chemistry Key Laboratory of Chemical Biology Ministry of Education;
Rega Institute for Medical Research Laboratory of Virology and Chemotherapy K.U. Leuven;
Rega Institute for Medical Research Laboratory of Virology and Chemotherapy K.U. Leuven;
Rega Institute for Medical Research Laboratory of Virology and Chemotherapy K.U. Leuven;
Centro de Biología Molecular “Severo Ochoa” (Consejo Superior de Investigaciones Científicas &
Department of Medicinal Chemistry Key Laboratory of Chemical Biology Ministry of Education;
Department of Medicinal Chemistry Key Laboratory of Chemical Biology Ministry of Education;
HAART; HIV-1 dual inhibitors; HIV-1 IN; RNase H; 5-hydroxypyrido2; 3-bpyrazin-6(5H)-one derivatives; Privileged structure;
机译:5-羟基吡啶[2,3- b]吡嗪-6(5h) - 衍生物作为HIV-1逆转录酶相关核糖核酸酶H和整合酶的新型双重抑制剂
机译:过去和未来。当前针对HIV-1整合酶和逆转录酶相关的核糖核酸酶H活性的药物:单和双活性位点抑制剂。
机译:发现二羟基吲哚-2-羧酸衍生物作为双变构HIV-1整合酶和逆转录酶相关核糖核酸酶H抑制剂
机译:二芳基苯胺衍生物作为HIV-1非核苷逆转录酶抑制剂的一类。
机译:A.关于通过自由基烯丙基化形成不对称四元中心的研究。 B.手性酰肼有机催化剂在Diels-Alder,氢化物还原和α-氯化反应中的应用。 C.针对潜在的HIV-1逆转录酶抑制剂的合成的研究:9-烷基芳基TIBO衍生物。
机译:支架跳跃和优化34-二羟基苯基 - 含硫基嘧啶酮:喹唑啉酮衍生物的合成作为HIV-1逆转录酶相关核糖核酸酶H的新型变形抑制剂
机译:茜素衍生物作为HIV-1逆转录酶相关DNA聚合酶和RNase H活性的新型双重抑制剂,对非核苷抗性逆转录酶的RNase H活性也有效