Reductions in Calcium Signaling Limit Inhibition to Diabetic Retinal Rod Bipolar Cells

摘要

PURPOSE. The balance of neuronal excitation and inhibition is important for proper retinal signaling. A previous report showed that diabetes selectively reduces light-evoked inhibition to the retinal dim light rod pathway, changing this balance. Here, changes in mechanisms of retinal inhibitory synaptic transmission after 6 weeks of diabetes are investigated.