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COMPOSITIONS FOR INDUCING DIFFERENTIATION INTO RETINAL CELLS FROM RETINAL PROGENITOR CELLS OR INDUCING PROLIFERATION OF RETINAL CELLS COMPRISING WNT SIGNALING PATHWAY ACTIVATORS
COMPOSITIONS FOR INDUCING DIFFERENTIATION INTO RETINAL CELLS FROM RETINAL PROGENITOR CELLS OR INDUCING PROLIFERATION OF RETINAL CELLS COMPRISING WNT SIGNALING PATHWAY ACTIVATORS
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机译:用于诱导从视网膜祖细胞分化为视网膜细胞或诱导包含WNT信号通路激活剂的视网膜细胞增殖的组合物
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摘要
Disclosed is a composition for inducing the proliferation of retinal cells or the differentiation of retinal progenitor cells into retinal cells. The composition, similar to in vivo conditions for development during embryogenesis, induces stem cells to differentiate into a multitude of photoreceptor cells at high yield within a short period of time, without an additional gene transfer. In addition, the differentiated photoreceptor cells are useful in cellular therapy because they, when transplanted into degenerated or injured retinas, can be engrafted and fused within the retinas to prevent or cure retinal degeneration.
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