Anaesthesia for thoracic and thoraco-abdominal aortic disease-Part 2: Anaesthetic management and neuroprotection

摘要

This article focuses on the intraoperative and postoperative management of these patients with special reference being made to neuroprotection. The actual choice of anaesthetic agents per se is much less important than the physiological principles applied to their use: there are several pharmacological 'recipes' that can be used, details of which can be found elsewhere.The site of aortic disease rather than its nature determines the clinical approach to these patients. The management of patients with proximal aortic disease (ascending aorta and aortic arch) is carried out with the use of full cardiopulmonary bypass and dominated by efforts to protect the brain with hypothermia with or without antegrade or retrograde cerebral perfusion. In patients with descending aortic disease the major focus is on controlling the adverse effects of aortic cross-clamping and unclamping, maintaining an adequate circulating volume and coagulation, and ensuring spinal cord and other distal organ perfusion. Partial bypassis sometimes used in these patients to allow blood flow to the lower body whilst the cross-clamp is applied. There are a number of differences in detail between centres, surgeons and anaesthetists in how the procedure is managed. It is therefore absolutely vital that the anaesthetist knows what the surgeon intends to do before the procedure begins.