A Computational Approach to Discovery of Novel Mutant p53 Reactivating Molecules As Targeted Radio-Sensitizing Agents for Head and Neck Cancer

Nikolaev A.; Zeng L.; Spencer S. A.; Bonner J. A.; Yang E. S.

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A Computational Approach to Discovery of Novel Mutant p53 Reactivating Molecules As Targeted Radio-Sensitizing Agents for Head and Neck Cancer

机译：用于发现新型突变体P53重新激活分子的计算方法，作为头部和颈部癌的靶向无线电敏化剂

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来源
《International Journal of Radiation Oncology, Biology, Physics 》 |2018年第3suppla期| 共2页
作者
Nikolaev A.; Zeng L.; Spencer S. A.; Bonner J. A.; Yang E. S.;
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作者单位

Univ Alabama Birmingham Dept Radiat Oncol Birmingham AL USA;

Univ Alabama Birmingham Birmingham AL USA;

Univ Alabama Birmingham Birmingham AL USA;

Univ Alabama Birmingham Birmingham AL USA;

Univ Alabama Birmingham Birmingham AL USA;

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正文语种 eng
中图分类放射医学 ;
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1. A Computational Approach to Discovery of Novel Mutant p53 Reactivating Molecules As Targeted Radio-Sensitizing Agents for Head and Neck Cancer [J] . Nikolaev A., Zeng L., Spencer S. A., International Journal of Radiation Oncology, Biology, Physics . 2018 ,第3Suppla期

机译：用于发现新型突变体P53重新激活分子的计算方法，作为头部和颈部癌的靶向无线电敏化剂
2. Modulation of interaction of mutant TP53 and wild type BRCA1 by alkaloids: a computational approach towards targeting protein-protein interaction as a futuristic therapeutic intervention strategy for breast cancer impediment [J] . Sameeksha Tiwari, Manika Awasthi, Swati Singh, Journal of Biomolecular Structure and Dynamics . 2018 ,第13a14期

机译：生物碱突变体TP53和野生型BRCA1的相互作用的调节：靶向蛋白质 - 蛋白质相互作用作为乳腺癌障碍未来派治疗干预策略的计算方法
3. Small Molecules Targeting Mutant P53: A Promising Approach for Cancer Treatment [J] . Elizabeth A. Lopes, Sara Gomes, Lucilia Saraiva, Current medicinal chemistry . 2019 ,第41期

机译：小分子靶向突变体p53：癌症治疗的有希望的方法
4. Investigating the details of oncogenic mutant p53 reactivation using FT-ICR Mass Spectrometry. [C] . David J. Clarke, Jenna Scotcher, Ted Hupp, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2012

机译：使用FT-ICR质谱法研究致癌突变体P53重新激活细节。
5. RS-41, A multi-targeted kinase inhibitor, induces cell cycle arrest and apoptosis in P53 mutant and wild type models of upper gastrointestinal cancers. [D] . Visal, Tanvi. 2017

机译：RS-41是一种多靶点激酶抑制剂，在上消化道癌的P53突变型和野生型模型中诱导细胞周期停滞和凋亡。
6. The p53-Reactivating Small Molecule RITA Induces Senescence in Head and Neck Cancer Cells [O] . Hui-Ching Chuang, Liang Peng Yang, Alison L. Fitzgerald, -1

机译：p53激活小分子RITA诱导头颈部癌细胞衰老。
7. A Computational Approach to Discovery of Novel Mutant p53 Reactivating Molecules As Targeted Radio-Sensitizing Agents for Head and Neck Cancer [O] . A. Nikolaev, L. Zeng, S.A. Spencer, 2018

机译：用于发现新型突变体P53重新激活分子的计算方法，作为头部和颈部癌的靶向无线电敏化剂

A Computational Approach to Discovery of Novel Mutant p53 Reactivating Molecules As Targeted Radio-Sensitizing Agents for Head and Neck Cancer

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