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Maternal cardiac function in preeclampsia.

机译:子痫前期的孕妇心脏功能。

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PURPOSE OF REVIEW: Acute cardiovascular complications affect 6% of severe preeclampsia and epidemiological studies demonstrate a strong association between preeclampsia and subsequent cardiovascular morbidity and mortality. This data suggests that not only can preeclampsia acutely impair cardiac function, but also it has the potential to provoke myocardial ischaemia and affect long-term cardiovascular health. This review highlights the recent insights on cardiovascular impairment in preeclampsia and postpartum. RECENT FINDINGS: Recent studies on preeclampsia have used newer echocardiographic indices that are more sensitive at detecting asymptomatic myocardial damage, better correlated to invasive indices of myocardial function and are predictive for subsequent cardiovascular morbidity. Current findings indicate an unexpectedly high prevalence of cardiac impairment in preeclampsia and postpartum. These findings have important implications for the long-term cardiovascular health of women whose pregnancies were complicated by preeclampsia. SUMMARY: Preeclampsia is associated with stage B heart failure (asymptomatic left ventricular dysfunction/hypertrophy), a high prevalence of essential hypertension and an increased cardiovascular risk status within few years postpartum. These findings are more prevalent with early onset/preterm preeclampsia. These cardiovascular findings are consistent with epidemiological studies showing a 'dose-dependent' relationship between preeclampsia and long-term cardiovascular morbidity and mortality. There is increasing evidence supporting the concept that a history of early onset/preterm preeclampsia should be taken into account to identify women at high cardiovascular risk even in the absence of other concomitant risk factors.
机译:审查的目的:急性心血管并发症占6%的严重先兆子痫,流行病学研究表明先兆子痫与随后的心血管疾病和死亡率之间存在密切的联系。这些数据表明,先兆子痫不仅会严重损害心脏功能,而且还可能引发心肌缺血并影响长期心血管健康。这篇综述强调了对子痫前期和产后心血管损害的最新见解。最新发现:子痫前期的最新研究使用了较新的超声心动图指标,这些指标在检测无症状心肌损伤时更加敏感,与心肌功能的侵入性指标相关性更高,并且可以预测随后的心血管疾病的发病率。目前的发现表明,子痫前期和产后心脏损害的发生率出乎意料地高。这些发现对怀孕并发先兆子痫的妇女的长期心血管健康具有重要意义。摘要:子痫前期与B期心力衰竭(无症状的左心功能不全/肥大),原发性高血压的高患病率以及产后几年内心血管疾病的患病率增加有关。这些发现在早发/早产先兆子痫中更为普遍。这些心血管发现与流行病学研究一致,流行病学研究表明先兆子痫与长期心血管疾病和死亡率之间存在“剂量依赖”关系。越来越多的证据支持这一观念,即即使没有其他伴随的危险因素,也应考虑早发/早产先兆子痫的病史,以识别出具有高心血管风险的妇女。

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