Synthesis and application of ortho-palladated complex of (4-phenylbenzoylmethylene)triphenylphosphorane as a highly active catalyst in the Suzuki cross-coupling reaction

摘要

The ortho-metallated complex [Pd(μ-Cl){κ_2(C,C)-[C _6H_4(PPh2CHC(O)C_6H _4-Ph-4)}]_2 (2a) was prepared by refluxing of Pd(OAc) _2 and {(Ph)_3PCHCOC_6H_4-Ph-4} (PhBPPY) of in CH_2Cl_2 followed by addition of an excess of KCl in MeOH Complex (2a) reacts with triphenylphosphine to give the mononuclear derivative [Pd(Cl)(PhC_6H_4COCHPPh_2C _6H_4)(PPh_3)] (3a) whose crystal structure has been determined by single crystal X-ray diffraction. The Suzuki reactions of aryl bromides and chlorides of varying electron density using complex (3a) as an efficient catalyst were performed, giving the cross-coupling products in good to excellent yields.