Biocompatible phosphatidylcholine bilayer coated on magnetic nanoparticles and their application in the extraction of several polycyclic aromatic hydrocarbons from environmental water and milk samples

摘要

In this work, phosphatidylcholine (PC) was coated on magnetic nanoparticles to form lipid bilayer as solid-phase extraction (SPE) sorbents for the enrichment of polycyclic aromatic hydrocarbons (PAHs) from environmental water and milk samples. The lipid bilayer was coated on Fe _3O _4 nanoparticles using a modified dry lipid film hydration method. The resulted Fe _3O _4/PC could be readily isolated from solution with a magnet, and exhibited excellent adsorption performance to organic pollutants. Only 0.1g of sorbents was enough to extract PAHs from 500mL aqueous solution, and 6mL of acetonitrile was required to desorb them. The method was fast and relied on 10min extraction time and 5min magnetic separation. The proposed method was successfully applied to determine PAHs in some environmental water and milk samples. The detection limit was in the range of 0.2-0.6ngL ~(-1). The recoveries of the spiked water samples ranged from 89% to 115% with relative standard deviations (RSD) varying from 1% to 8%. For spiked milk samples, RSD was satisfactory (1-9%), but the recoveries were relatively low (42-62%). We show the potentials of Fe _3O _4/PC sorbents in environmental water and biological sample analyses.