Critical appraisal of locoregional failure and systemic disease progression after preoperative chemoradiation of esophageal adenocarcinoma

摘要

To the Editor: We commend Sudo et al1 on their effort to retrospectively analyze their surveillance strategy of patients after trimodality therapy (TMT) for adenocarcinoma of the esophagus or esophagogastric junction (EAC). Overall, the presented results are widely confirmed by our own experience with locally advanced EAC that is treated by preop-erative chemotherapy followed by surgery in our institution. Using a similarly aggressive surveillance strategy, we found 2% locoregional failure (LRF) only and approximately 20% distant metastases (with or without LRF) in 567 patients treated between 2000 and 2010. However, we also have some concerns about the article by Sudo et al.