Boronic acid-based thin films that show saccharide-responsive multicolor changes

摘要

A novel saccharide sensor that displays a distinct color change resembling a traffic signal was developed. By copolymerizing boronic acid and amine monomers on a glass plate, a boronic acid-containing thin film was obtained. Anionic blue and yellow dyes were adsorbed on the thin film, and the film was immersed in aqueous saccharide solutions containing a cationic red dye. With increase in the saccharide concentration in the solution, the thin film changes color from green to red via yellow. The observed distinct changes in color were attributed to a stepwise release and binding of dyes. The sensitivity of the saccharide sensor was dependent on the monomer composition of the thin film and increased with increasing the boronic acid content. The pH of the saccharide solution was another key factor affecting the sensing behavior, and glucose-responsive color changes were significantly enhanced at pH 7.8. By optimizing these conditions, significant color changes in response to glucose were achieved. Saccharide selectivity was found to be in the following order: fructose>glucose>galactose=mannose>sucrose. (c) 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 42679.