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Controlled Release Properties of Zein-Fatty Acid Blend Films for Multiple Bioactive Compounds

机译:玉米蛋白-脂肪酸混合膜对多种生物活性化合物的控释性能

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摘要

To develop edible films having controlled release properties for multiple bioactive compounds, hydrophobicity and morphology of zein films were modified by blending zein with oleic (C_(18:1))Δ~9, linoleic (C_(18:2))Δ~(9,12), or lauric (C_(12)) acids in the presence of lecithin. The blend zein films showed 2—8.5- and 1.6—2.9-fold lower initial release rates for the model active compounds, lysozyme (LYS) and (+)-catechin (CAT), than the zein control films, respectively. The change of fatty acid chain length affected both CAT and LYS release rates while the change of fatty acid double bond number affected only the CAT release rate. The film morphologies suggested that the blend films owe their controlled release properties mainly to the microspheres formed within their matrix and encapsulation of active compounds. The blend films showed antilisterial activity and antioxidant activity up to 81 μmol Trolox/cm~2. The controlled release of multiple bioactive compounds from a single film showed the . possibility of combining application of active and bioactive packaging technologies and improving not only safety and quality but also health benefits of packed food.
机译:为了开发对多种生物活性化合物具有控释特性的可食用膜,通过将玉米醇溶蛋白与油酸(C_(18:1))Δ〜9,亚油酸(C_(18:2))Δ〜(共混)来改性玉米醇溶蛋白膜的疏水性和形态。 9,12)或在卵磷脂存在下的月桂酸(C_(12))酸。混合玉米醇溶蛋白膜显示的模型活性化合物溶菌酶(LYS)和(+)-儿茶素(CAT)的初始释放速率分别比玉米醇溶蛋白对照膜低2-8.5倍和1.6-2.9倍。脂肪酸链长的变化影响CAT和LYS的释放速率,而脂肪酸双键数的变化仅影响CAT的释放速率。膜的形态表明,共混膜的控释性能主要归因于其基质内形成的微球和活性化合物的包封。共混膜的抗李斯特活性和抗氧化活性最高达到81μmolTrolox / cm〜2。从单个薄膜中释放多种生物活性化合物的行为显示。结合使用主动和生物活性包装技术的可能性,不仅可以提高包装食品的安全性和质量,而且还可以改善健康状况。

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