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Oat β-Glucan Increased ATPases Activity and Energy Charge in Small Intestine of Rats

机译:燕麦β-葡聚糖增加大鼠小肠ATPases活性和能量电荷

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Dietary oat or oat products may potentially help to fight against high risk of cardiovascular diseases and β-glucan in oat was considered as a central player. The present study aimed to investigate the effects of dietary oat whole meal or β-glucan on insulin sensitivity and energy metabolism of rats. Rats were fed with control diet, oat whole meal based diet, or control diet with supplemented β-glucan for 4 weeks. Oat whole meal and β-gIucan increased insulin sensitivity index. Interestingly, supplementation of oat whole meal or β-glucan induced increases in intestinal Na~+K~+-ATPase activity, Ca~(2+)Mg~(2+)-ATPase activity, and energy charge, particularly in the distal part of small intestine (ileum). Furthermore, amounts of Bifidobacterium and Lactobacillus in colon contents were elevated by oat whole meal or β-glucan. These findings provide an insight into that β-glucan increased insulin sensitivity and benefited intestinal health.
机译:膳食燕麦或燕麦产品可能有助于抗击心血管疾病的高风险,燕麦中的β-葡聚糖被认为是主要参与者。本研究旨在探讨全麦膳食饮食或β-葡聚糖对大鼠胰岛素敏感性和能量代谢的影响。给大鼠喂食对照饮食,基于燕麦全餐的饮食或补充β-葡聚糖的对照饮食4周。燕麦全餐和β-葡聚糖可增加胰岛素敏感性指数。有趣的是,补充燕麦全餐或β-葡聚糖诱导的肠道Na〜+ K〜+ -ATPase活性,Ca〜(2+)Mg〜(2 +)-ATPase活性和能量电荷增加,特别是在远端小肠(回肠)。此外,通过燕麦全餐或β-葡聚糖可提高结肠中双歧杆菌和乳杆菌的含量。这些发现提供了对β-葡聚糖增加胰岛素敏感性并有益于肠道健康的见解。

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