Gradual reduction vs abrupt cessation as a smoking cessation strategy in smokers who want to quit

摘要

US guidelines1 and US Food and Drug Administration labeling recommend smokers quit abruptly, based on data from observational studies.2 However, gradual cessation is popular3 and may be effective when structured as part of an intervention.4 This alternative method of quitting could improve the uptake of effective treatments. This JAMA Clinical Evidence Synopsis summarizes a Coch-rane review5 of the evidence from randomized trials of smokers who wanted to quit using a gradual reduction in smoking vs an abrupt cessation strategy.