De Novo Anti-HLA DSA Characteristics and Subclinical Antibody-Mediated Kidney Allograft Injury

Yamamoto Takayuki; Watarai Yoshihiko; Takeda Asami; Tsujita Makoto; Hiramitsu Takahisa; Goto Norihiko; Narumi Shunji; Katayama Akio; Morozumi Kunio; Uchida Kazuharu; Kobayashi Takaaki

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De Novo Anti-HLA DSA Characteristics and Subclinical Antibody-Mediated Kidney Allograft Injury

机译：从头抗HLA DSA特征和亚临床抗体介导的肾脏同种异体移植损伤

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Background It is unclear whether all donor-specific antibodies (DSA) can cause chronic antibody-mediated rejection (AMR). Subclinical stage before manifestation of renal dysfunction may be a critical period for reversing AMR. The aim of our study was to identify factors related to the development of subclinical AMR and to clarify the characteristics of de novo DSA.

机译：背景技术目前尚不清楚是否所有供体特异性抗体（DSA）都能引起慢性抗体介导的排斥反应（AMR）。肾功能不全之前的亚临床阶段可能是逆转AMR的关键时期。我们研究的目的是确定与亚临床AMR发展相关的因素，并阐明从头DSA的特征。

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《Transplantation: Official Journal of the Transplantation Society 》 |2016年第10期| 共9页
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Yamamoto Takayuki; Watarai Yoshihiko; Takeda Asami; Tsujita Makoto; Hiramitsu Takahisa; Goto Norihiko; Narumi Shunji; Katayama Akio; Morozumi Kunio; Uchida Kazuharu; Kobayashi Takaaki;
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1. De Novo Anti-HLA DSA Characteristics and Subclinical Antibody-Mediated Kidney Allograft Injury [J] . Yamamoto Takayuki, Watarai Yoshihiko, Takeda Asami, Transplantation: Official Journal of the Transplantation Society . 2016 ,第10期

机译：从头抗HLA DSA特征和亚临床抗体介导的肾脏同种异体移植损伤
2. PREVALENCE AND CLINICAL IMPACT OF DE NOVO DONOR SPECIFIC ANTI-HLA ANTIBODIES (DN DSA) IN PEDIATRIC KIDNEY TRANSPLANTATION IN GREECE [J] . Fylaktou Asimina, Mitsioni Andromachi, Vittoraki Angeliki, Transplant international : . 2019 ,第S2期

机译：De Novo供体特异性抗HLA抗体（DN DSA）在希腊小儿肾移植中的患病率和临床影响
3. Non-Complement-Binding De Novo Donor-Specific Anti-HLA Antibodies and Kidney Allograft Survival [J] . Gwendaline Guidicelli, Florent Guerviile, Sebastien Lepreux, Journal of the American Society of Nephrology: JASN . 2016 ,第2期

机译：非补体结合De Novo Novo供体特异性抗HLA抗体和肾同种异体移植物存活
4. RELEVANCE OF DIFFERENT ANTIBODY DETECTION METHODS FOR PREDICTION OF ANTIBODY MEDIATED REJECTION OF DECEASED DONOR KIDNEY ALLOGRAFTS [C] . Adriana I. Colovai, George Vlad, Eric K. Ho, Clinical Histocompatibility Workshop. . 2009

机译：不同抗体检测方法的相关性，用于预测抗体介导的死亡肾同种异体移植物的抑制作用
5. Characteristics of Donor-Specific anti-HLA Antibodies (DSA) Impacting different Renal Allograft Outcomes. [D] . Ghandorah, Salim S. 2015

机译：供体特异性抗HLA抗体（DSA）的特性会影响不同的同种异体肾移植结果。
6. Intensity of de novo DSA detected by Immucor Lifecodes assay and C3d fixing antibodies are not predictive of subclinical ABMR after Kidney Transplantation [O] . Dominique Bertrand, Rangolie Kaveri, Charlotte Laurent, 2021

机译：由Dumucer Lifecode测定和C3D固定抗体检测到的DE Novo DSA的强度并未预测肾移植后的亚临床ABMR
7. Case Report: Splenic Irradiation for the Treatment of Chronic Active Antibody-Mediated Rejection in Kidney Allograft Recipients With De Novo Donor-Specific Antibodies [O] . Lan Zhu, Zhiliang Guo, Rula Sa, 2021

机译：病例报告：用DE Novo供体特异性抗体治疗肾同种异体移植受者慢性活性抗体介导的抑制的脾照射

De Novo Anti-HLA DSA Characteristics and Subclinical Antibody-Mediated Kidney Allograft Injury

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