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Urinary exosome-derived miRNA gene biomarkers for diagnosis of antibody-mediated rejection in kidney allografts and use thereof

机译:用于诊断肾同种异体移植物中抗体介导的抗体介导的抗体介导的抑制的尿液细胞组衍生的miroNA基因生物标志物

摘要

The present invention relates to a urine exosome-derived miRNA gene biomarker and its use for diagnosis of antibody-mediated rejection after kidney transplantation, and more particularly, antibody-mediated rejection (ABMR) after kidney transplantation. It relates to a biomarker, a composition for diagnosing an antibody-mediated rejection reaction, a kit, a method for providing information for diagnosis of an antibody-mediated rejection reaction using the same, and a screening method for an antibody-mediated rejection treatment agent.
机译:本发明涉及尿液外衍生的miRNA基因生物标志物及其用于肾移植后诊断抗体介导的排斥反应,更具体地,肾移植后的抗体介导的排斥(ABMR)。它涉及一种生物标志物,一种用于诊断抗体介导的排斥反应的组合物,试剂盒,用于提供使用相同抗体介导的排斥反应的信息的方法,以及抗体介导的排斥处理剂的筛选方法。

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