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Case Report Demonstrating the Safe and Effective Means of Expanding the Donor Pool With Livers Recovered From Brain-Dead Donors After Ethylene Glycol Toxicity

机译:案例报告证明了乙二醇毒性后扩大从脑死亡的供体中回收的肝脏以扩大供体库的安全有效方法

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摘要

The growing disparity between organ supply and demand has become the greatest hurdle facing transplant professionals and life-saving transplants. Because the organ shortage has become the rate-limiting step to effective transplants, it is critical for the transplant community to identify viable mechanisms to expand the donor pool and use every available allograft. Although using kidneys from deceased donors whose demise was secondary to ethylene glycol (EG) toxicity requires great deliberation and precise timing as described by Barbas et al [5], using hepatic allografts in this setting involves far less risk. The following is a discussion of a 61-year-old male who was diagnosed with end-stage liver disease secondary to non-alcoholic steatohepatitis and ultimately underwent a life-saving transplant with a liver recovered from a donor with EG-induced brain death and allocated nationally due to trepidation by local and regional centers to use the liver from a donor after EG toxicity.
机译:器官供求之间的差距日益扩大,已成为移植专业人员和挽救生命的移植工作面临的最大障碍。由于器官短缺已成为有效移植的限速步骤,因此对于移植界来说,确定可行的机制以扩大供体库并使用每种可用的同种异体移植至关重要。尽管如Barbas等[5]所描述的那样,使用死于乙二醇(EG)继发性死亡的供者的肾脏需要进行认真的思考和准确的时机,但在这种情况下使用肝同种异体移植的风险要小得多。以下是对一名61岁男性的讨论,该男性被诊断出患有非酒精性脂肪性肝炎继发的终末期肝病,并最终进行了挽救生命的移植手术,并从一名供体中回收了肝脏,并导致了EG引起的脑死亡和由于地方和地区中心不满而在全国范围内分配,以在EG毒性后使用供体的肝脏。

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