TNF inhibitor infection risk coupled with lower CV risk

摘要

Tumour necrosis factor (TNF) inhibitors increase patients' risk of being admitted to hospital for infection,but appear to reduce their cardiovascular risk,two studies presented at the Annual European Congress of Rheumatology in Amsterdam last week suggest.Johan Askling,from the Karolinska Institute in Stockholm,used the Swedish in-patient register to examine hospital admissions for infection and the Swedish programme that monitors biologics in rheumatoid arthritis to look at the admission rates among those taking TNF inhibitors.They found that,of 4,160 patients taking TNF inhibitors,2,465 were admitted to hospital for infection and calculated that TNF inhibitors were associated with a 39 per cent increased risk of being admitted to hospital for infection (adjusted relative risk 1.39;95 per cent confidence interval 1.23-1.57).