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Stillbirths: rates, risk factors, and acceleration towards 2030

机译:死产:比率,风险因素和到2030年的加速发展

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An estimated 2.6 million third trimester stillbirths occurred in 2015 (uncertainty range 2.4-3.0 million). The number of stillbirths has reduced more slowly than has maternal mortality or mortality in children younger than 5 years, which were explicitly targeted in the Millennium Development Goals. The Every Newborn Action Plan has the target of 12 or fewer stillbirths per 1000 births in every country by 2030. 94 mainly high-income countries and upper middle-income countries have already met this target, although with noticeable disparities. At least 56 countries, particularly in Africa and in areas affected by conflict, will have to more than double present progress to reach this target. Most (98%) stillbirths are in low-income and middle-income countries. Improved care at birth is essential to prevent 1.3 million (uncertainty range 1.2-1.6 million) intrapartum stillbirths, end preventable maternal and neonatal deaths, and improve child development. Estimates for stillbirth causation are impeded by various classification systems, but for 18 countries with reliable data, congenital abnormalities account for a median of only 7.4% of stillbirths. Many disorders associated with stillbirths are potentially modifiable and often coexist, such as maternal infections (population attributable fraction: malaria 8.0% and syphilis 7.7%), non-communicable diseases, nutrition and lifestyle factors (each about 10%), and maternal age older than 35 years (6.7%). Prolonged pregnancies contribute to 14.0% of stillbirths. Causal pathways for stillbirth frequently involve impaired placental function, either with fetal growth restriction or preterm labour, or both. Two-thirds of newborns have their births registered. However, less than 5% of neonatal deaths and even fewer stillbirths have death registration. Records and registrations of all births, stillbirths, neonatal, and maternal deaths in a health facility would substantially increase data availability. Improved data alone will not save lives but provide a way to target interventions to reach more than 7000 women every day worldwide who experience the reality of stillbirth.
机译:2015年,估计有260万例孕晚期死胎(不确定性范围为2.4-300万)。死产人数减少的速度比产妇死亡率或5岁以下儿童的死亡率下降得慢,这是千年发展目标明确规定的目标。 《每个新生儿行动计划》的目标是到2030年每个国家每1000名婴儿中有12个或更少的死产。94个主要的高收入国家和中等偏上收入国家已经实现了这一目标,尽管差距明显。至少有56个国家,特别是在非洲和受冲突影响地区的国家,必须将目前的进展翻番,才能实现这一目标。大多数(98%)死产在低收入和中等收入国家。改善出生时的护理对于防止130万(不确定范围在1.2-160万之间)产中死产,结束可预防的孕产妇和新生儿死亡以及改善儿童发育至关重要。死产原因的估计受到各种分类系统的阻碍,但是对于有可靠数据的18个国家,先天性异常仅占死产的中位数7.4%。与死产有关的许多疾病可能是可以改变的,并且常常并存,例如产妇感染(人口可归因的比例:疟疾8.0%和梅毒7.7%),非传染性疾病,营养和生活方式因素(每个约10%)以及产妇年龄较大超过35岁(6.7%)。长时间怀孕占死产的14.0%。死产的成因途径通常涉及胎盘功能受损,可能是胎儿生长受限或早产,或两者兼而有之。三分之二的新生儿有出生记录。但是,只有不到5%的新生儿死亡和更少的死产有了死亡登记。在医疗机构中记录和记录所有出生,死产,新生儿和产妇死亡,将大大提高数据的可用性。仅靠改善数据并不能挽救生命,而是可以提供一种针对性干预措施,使每天有7,000名经历死产现实的妇女受益。

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