Prescription of physical activity: an undervalued intervention

摘要

In The Lancet, Peter Kokkinos and colleagues1 add to the large body of work on the benefits of physical activity or fitness for health, by showing an inverse association between fitness and all-cause mortality in 10043 individuals with dyslipidaemia. Irrespective of whether patients were prescribed statins, the physically fittest participants had a 60-70% reduction in all-cause mortality rates during follow-up, compared with the least fit participants (HR for patients taking statins 0-32, 95% Cl 0-23-0-45; HR for patients not taking statins 0-37, 0-31-0-44). Strikingly, patients not prescribed statins but who were highly fit still had a significantly lower risk of mortality than those taking statins, but who were unfit (HR 0-53, 95% Cl 0-44-0-65).1 Patients who were taking statins and were physically fit had the lowest mortality risk (0-30,0-21-0-41).