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Protective Effect of Palmitoylethanolamide in a Rat Model of Cystitis

机译:棕榈酰乙醇酰胺对膀胱炎大鼠模型的保护作用

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Purpose: PEA is an endogenous mediator released together with the endo-cannabinoid anandamide from membrane phospholipids. It is a plant derived compound with analgesic and anti-inflammatory properties. We verified whether the pathophysiology of experimental cystitis involves changes in the levels of PEA and of some of its targets, ie CB1 and CB2 receptors, and PPAR. We also determined whether exogenously administered PEA could be proposed as a preventive measure for cystitis.
机译:目的:PEA是一种与内源性大麻素一起从膜磷脂中释放出来的内源性介质。它是一种具有镇痛和抗炎特性的植物来源化合物。我们验证了实验性膀胱炎的病理生理学是否涉及PEA及其某些靶标(即CB1和CB2受体以及PPAR)水平的变化。我们还确定了是否可以建议使用外源性PEA作为膀胱炎的预防措施。

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