Copper-catalyzed heteroannulation: a simple route to the synthesis of pyrrolo[2,3-b]carbazole and pyrrolo[2,3-b]quinoline derivatives

摘要

A simple and efficient method for the synthesis of biologically important pyrrolo[2,3-b]carbazoles and pyrrolo[2,3-b]quinolines is described. This involves the reaction of corresponding carbazole or quinoline-1,2-haloaldehyde with isocyanoacetate via copper catalyzed heteroannulation in good yields. (C) 2014 Elsevier Ltd. All rights reserved.