首页> 外国专利> Pyrrolo (3,4-c) carbazole and pyrido (2,3-b) pyrrolo (3,4-e) indole derivatives, preparation method and pharmaceutical compositions containing same

Pyrrolo (3,4-c) carbazole and pyrido (2,3-b) pyrrolo (3,4-e) indole derivatives, preparation method and pharmaceutical compositions containing same

机译:吡咯罗(3,4-c)咔唑和吡啶基(2,3-b)吡咯罗(3,4-e)吲哚衍生物,制备方法和含有它们的药物组合物

摘要

A compound selected from those of formula (I): embedded imagewherein: Z represents a group of the formula U-V as defined in the description, W1 represents together with carbon to which it is bonded, phenyl, pyridyl, W2 is as defined in the description, X1, X2 each represents hydrogen, hydroxy, alkoxy, mercapto or alkylthio, Y1, Y2 each represents hydrogen, or X1 and Y1, X2 and Y2 with carbon carrying them, together form carbonyl or thiocarbonyl, R1 is as defined in the description, Q represents oxygen, a group NR2 as defined in the description, its isomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful in the treatment of cancer.
机译:选自式(I)的那些的化合物: <图像alt =“嵌入式图像” file =“ US20060004428A1-20060105-C00001.GIF” he =“ 32.51mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 69.93mm“ /> 其中:Z代表说明书中定义的式U-V的基团, W 1 与其所键合的碳,苯基,吡啶基, W < Sub> 2 如描述中所定义, X 1 ,X 2 每个代表氢,羟基,烷氧基,巯基或烷硫基, Y 1 ,Y 2 每个代表氢, 或X 1 和Y 1 ,X 2 和Y 2 ,碳携带它们,一起形成羰基或硫代羰基, R 1 如描述中所定义, Q代表氧,NR 2 组为def本说明书中所定义的,其异构体及其与药学上可接受的酸或碱的加成盐,以及含有该异构体的药用产品,可用于治疗癌症。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号